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View Structure Prediction Details

Protein: nxt3
Organism: Schizosaccharomyces pombe
Length: 434 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nxt3.

Description E-value Query
Range
Subject
Range
gi|109488113 - gi|109488113|ref|XP_340803.2| PREDICTED: similar to Ras-GTPase-activating protein binding protein 1 ...
207.0 [0..3] [395..58]
gi|74139958 - gi|74139958|dbj|BAE31814.1| unnamed protein product [Mus musculus]
207.0 [0..1] [394..62]
gi|40788318 - gi|40788318|dbj|BAA31635.2| KIAA0660 protein [Homo sapiens]
200.0 [0..1] [394..2]
gi|114602973 - gi|114602973|ref|XP_001169085.1| PREDICTED: Ras-GTPase-activating protein SH3-domain-binding protein...
200.0 [0..8] [407..1]
gi|109079425 - gi|109079425|ref|XP_001110776.1| PREDICTED: Ras-GTPase-activating protein SH3-domain-binding protein...
200.0 [0..8] [407..1]
gi|68354694 - gi|68354694|ref|XP_683065.1| PREDICTED: similar to MGC81268 protein isoform 1 [Danio rerio]
199.0 [0..8] [418..1]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAENATLLE PVLGKDEIGW MFVQEYYTYL NKEPNRLHCF YTKKSTLIHG DEGESISLCH  60
   61 GQQEIHNKIL DLDFQNCKVL ISNVDSLASS NGGIVIQVLG EMSNKGKLSR KFAQTFFLAE 120
  121 QPNGYFVLND IFRFLRED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1a2kA
Description: Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.74084472095013 bayes_pls_golite062009
binding 1.29138202593822 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.983337869604082 bayes_pls_golite062009
protein transporter activity 0.960383711156379 bayes_pls_golite062009
kinase activity 0.871357091497469 bayes_pls_golite062009
protein serine/threonine kinase activity 0.797931524291551 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.662760637049546 bayes_pls_golite062009
protein kinase activity 0.622060011038738 bayes_pls_golite062009
transporter activity 0.55283159394909 bayes_pls_golite062009
Ran GTPase binding 0.437541267934309 bayes_pls_golite062009
transferase activity 0.250005906709975 bayes_pls_golite062009
nucleic acid binding 0.0725168535072961 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [139-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEEEEESPDA VEKEKKDVAS EPYVNGVQSQ EHLPSAKEEG HYQDPAATEN NFATAALISN  60
   61 E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [200-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDSLNQATLA VPEEPVIQVT EASVPSFVSQ QENQLQDEAL TSNSKNADAI GASDANVATA  60
   61 PKSWADLIAR NHPDVKSQAS VSSTASTTGQ TVKGVNADQT QQPTAPYTQS NELLETSVFV 120
  121 KNIPPETSDV SLKSAMSIFG PVKAIEFARR KGTAYVDFVN HECVQLALNK KTLQINNATL 180
  181 NIEERRRLFS GKFNKSGDKK SNDNYNGMKR NFRKGNRGAF DGRSKEVTTS KKQNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.30103
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.43517729895315 bayes_pls_golite062009
binding 2.41127885655304 bayes_pls_golite062009
RNA binding 1.96321378335448 bayes_pls_golite062009
protein binding 1.52056358240529 bayes_pls_golite062009
mRNA binding 0.79383576791259 bayes_pls_golite062009
small conjugating protein ligase activity 0.681978520687901 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.494091580976874 bayes_pls_golite062009
acid-amino acid ligase activity 0.257073928625242 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle