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View Structure Prediction Details

Protein: nxt3
Organism: Schizosaccharomyces pombe
Length: 434 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nxt3.

Description E-value Query
Range
Subject
Range
gi|109488113 - gi|109488113|ref|XP_340803.2| PREDICTED: similar to Ras-GTPase-activating protein binding protein 1 ...
207.0 [0..3] [395..58]
gi|74139958 - gi|74139958|dbj|BAE31814.1| unnamed protein product [Mus musculus]
207.0 [0..1] [394..62]
gi|40788318 - gi|40788318|dbj|BAA31635.2| KIAA0660 protein [Homo sapiens]
200.0 [0..1] [394..2]
gi|114602973 - gi|114602973|ref|XP_001169085.1| PREDICTED: Ras-GTPase-activating protein SH3-domain-binding protein...
200.0 [0..8] [407..1]
gi|109079425 - gi|109079425|ref|XP_001110776.1| PREDICTED: Ras-GTPase-activating protein SH3-domain-binding protein...
200.0 [0..8] [407..1]
gi|68354694 - gi|68354694|ref|XP_683065.1| PREDICTED: similar to MGC81268 protein isoform 1 [Danio rerio]
199.0 [0..8] [418..1]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAENATLLE PVLGKDEIGW MFVQEYYTYL NKEPNRLHCF YTKKSTLIHG DEGESISLCH  60
   61 GQQEIHNKIL DLDFQNCKVL ISNVDSLASS NGGIVIQVLG EMSNKGKLSR KFAQTFFLAE 120
  121 QPNGYFVLND IFRFLRED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1a2kA
Description: Nuclear transport factor-2 (NTF2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.74084472095013 bayes_pls_golite062009
binding 1.29138202593822 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.983337869604082 bayes_pls_golite062009
protein transporter activity 0.960383711156379 bayes_pls_golite062009
kinase activity 0.871357091497469 bayes_pls_golite062009
protein serine/threonine kinase activity 0.797931524291551 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.662760637049546 bayes_pls_golite062009
protein kinase activity 0.622060011038738 bayes_pls_golite062009
transporter activity 0.55283159394909 bayes_pls_golite062009
Ran GTPase binding 0.437541267934309 bayes_pls_golite062009
transferase activity 0.250005906709975 bayes_pls_golite062009
nucleic acid binding 0.0725168535072961 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [139-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEEEEESPDA VEKEKKDVAS EPYVNGVQSQ EHLPSAKEEG HYQDPAATEN NFATAALISN  60
   61 E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [200-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDSLNQATLA VPEEPVIQVT EASVPSFVSQ QENQLQDEAL TSNSKNADAI GASDANVATA  60
   61 PKSWADLIAR NHPDVKSQAS VSSTASTTGQ TVKGVNADQT QQPTAPYTQS NELLETSVFV 120
  121 KNIPPETSDV SLKSAMSIFG PVKAIEFARR KGTAYVDFVN HECVQLALNK KTLQINNATL 180
  181 NIEERRRLFS GKFNKSGDKK SNDNYNGMKR NFRKGNRGAF DGRSKEVTTS KKQNN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.30103
Match: 1cvjA
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 2.43517729895315 bayes_pls_golite062009
binding 2.41127885655304 bayes_pls_golite062009
RNA binding 1.96321378335448 bayes_pls_golite062009
protein binding 1.52056358240529 bayes_pls_golite062009
mRNA binding 0.79383576791259 bayes_pls_golite062009
small conjugating protein ligase activity 0.681978520687901 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.494091580976874 bayes_pls_golite062009
acid-amino acid ligase activity 0.257073928625242 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle