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View Structure Prediction Details

Protein: csn3
Organism: Schizosaccharomyces pombe
Length: 334 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for csn3.

Description E-value Query
Range
Subject
Range
gi|108871514, gi... - gi|157131502|ref|XP_001662261.1| 26S proteasome regulatory subunit S3 [Aedes aegypti], gi|108871514|...
308.0 [0..12] [325..141]
PSMD3_ANOST - Probable 26S proteasome non-ATPase regulatory subunit 3 OS=Anopheles stephensi GN=DOXA2 PE=3 SV=1
308.0 [0..12] [325..148]
PSMD3_ANOGA - Probable 26S proteasome non-ATPase regulatory subunit 3 OS=Anopheles gambiae GN=Dox-A2 PE=3 SV=2
gi|55235415, gi|... - gi|58393108|ref|XP_319831.2| AGAP009082-PA [Anopheles gambiae str. PEST], gi|55235415|gb|EAA14736.2|...
303.0 [0..12] [325..144]
PSD3_ANOGA - (O61470) Probable 26S proteasome non-ATPase regulatory subunit 3 (26S proteasome subunit S3) (Diphen...
302.0 [0..12] [325..144]
gi|88175752, gi|... - gi|88175752|gb|EAQ83220.1| hypothetical protein CHGG_09624 [Chaetomium globosum CBS 148.51], gi|1162...
302.0 [0..17] [325..170]
gi|32421113, gi|... - gi|32421113|ref|XP_331000.1| hypothetical protein [Neurospora crassa], gi|28921083|gb|EAA30401.1| hy...
gi|85093155 - gi|85093155|ref|XP_959637.1| hypothetical protein NCU02224 [Neurospora crassa OR74A]
302.0 [0..17] [325..190]
gi|8778979, gi|2... - gi|8778979|gb|AAF79894.1|AC022472_3 Contains similarity to 26s proteasome regulatory subunit S3 from...
300.0 [0..14] [334..168]
gi|66546020 - gi|66546020|ref|XP_623947.1| PREDICTED: similar to Probable 26S proteasome non-ATPase regulatory sub...
299.0 [0..13] [334..143]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFQGTLPFH PLEDPETLLL KFTDFVHQHS VEQCNQLSMY IIASVNSLAE AFYGSHPEKY  60
   61 NIVFQSVEYA AHSPAISVMH VCYLKELLRQ GQYATSLKSF NDLEVSKHIP GSILLQYCMY 120
  121 AAYHCLGNND L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [132-241]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSAKVWYFSI LYIPTTTLTS FHEEAYYSFL LLYIITTGKK FQLDSATSSN VLPLKRHMVP  60
   61 YEEFLDAYLK DVNTLRTVIK EHWSRFLKDN STAFILFALE VYPMHRLKKW 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.503 0.918 cytosol a.1.1 Globin-like

Predicted Domain #3
Region A:
Residues: [242-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKTFSSLKLE YIAKQLAISQ DVAKEIIQKF DNKTNFTVAN GEIFLTFNAL DDVSPEMHSD  60
   61 LCQQLIEASK NFEASIRLKS VIYSKIMAKK LNA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1ufmA
Description: Solution structure of the PCI domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.76121492612224 bayes_pls_golite062009
DNA binding 4.45042383195146 bayes_pls_golite062009
nucleic acid binding 4.3254009446371 bayes_pls_golite062009
transcription factor activity 3.7855017556511 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
sequence-specific DNA binding 2.23304004014963 bayes_pls_golite062009
transcription activator activity 2.05043065144612 bayes_pls_golite062009
transcription repressor activity 1.93737634607471 bayes_pls_golite062009
small conjugating protein ligase activity 1.27763700765562 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.23862224095769 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.12147035668008 bayes_pls_golite062009
acid-amino acid ligase activity 0.754042916649094 bayes_pls_golite062009
protein binding 0.753698599635855 bayes_pls_golite062009
transcription factor binding 0.612315945412079 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.249771970501337 bayes_pls_golite062009
hydrolase activity 0.140191206949582 bayes_pls_golite062009
transferase activity 0.064832527337659 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle