| Protein: | clr4 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 490 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for clr4.
| Description | E-value | Query Range |
Subject Range |
|
|
316.0 | [0..1] | [490..1] |
|
|
231.0 | [0..6] | [489..157] |
|
|
223.0 | [0..148] | [489..940] |
|
|
220.0 | [0..6] | [489..199] |
|
|
219.0 | [0..3] | [489..214] |
|
|
216.0 | [0..188] | [485..959] |
|
|
215.0 | [0..188] | [485..955] |
|
Region A: Residues: [1-88] |
1 11 21 31 41 51
| | | | | |
1 MSPKQEEYEV ERIVDEKLDR NGAVKLYRIR WLNYSSRSDT WEPPENLSGC SAVLAEWKRR 60
61 KRRLKGSNSD SDSPHHASNP HPNSRQKH
|
| Detection Method: |  |
| Confidence: | 8.09691 |
| Match: | 1g6zA |
| Description: | Histone methyltransferase clr4, chromo domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription repressor activity | 4.08500855631983 | bayes_pls_golite062009 |
| transcription regulator activity | 3.64390820819794 | bayes_pls_golite062009 |
| methylated histone residue binding | 3.42338304360938 | bayes_pls_golite062009 |
| chromatin binding | 3.1924157640698 | bayes_pls_golite062009 |
| binding | 3.06758476214113 | bayes_pls_golite062009 |
| nucleic acid binding | 2.19167058827256 | bayes_pls_golite062009 |
| DNA binding | 2.05514577638135 | bayes_pls_golite062009 |
| histone binding | 2.00388175060339 | bayes_pls_golite062009 |
| protein binding | 1.61683263008775 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.998957812785999 | bayes_pls_golite062009 |
| general transcriptional repressor activity | 0.75184432495983 | bayes_pls_golite062009 |
| DNA helicase activity | 0.726970683178132 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.494788451379878 | bayes_pls_golite062009 |
| RNA binding | 0.460026444989124 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.294457188332415 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.208144053427115 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.16478533243377 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.154199885836329 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.151644275982344 | bayes_pls_golite062009 |
| catalytic activity | 0.14067200158938 | bayes_pls_golite062009 |
| transcription activator activity | 0.136090220479238 | bayes_pls_golite062009 |
|
Region A: Residues: [89-201] |
1 11 21 31 41 51
| | | | | |
1 QHQTSKSVPR SQRFSRELNV KKENKKVFSS QTTKRQSRKQ STALTTNDTS IILDDSLHTN 60
61 SKKLGKTRNE VKEESQKREL VSNSIKEATS PKTSSILTKP RNPSKLDSYT HLS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [202-490] |
1 11 21 31 41 51
| | | | | |
1 FYEKRELFRK KLREIEGPEV TLVNEVDDEP CPSLDFQFIS QYRLTQGVIP PDPNFQSGCN 60
61 CSSLGGCDLN NPSRCECLDD LDEPTHFAYD AQGRVRADTG AVIYECNSFC SCSMECPNRV 120
121 VQRGRTLPLE IFKTKEKGWG VRSLRFAPAG TFITCYLGEV ITSAEAAKRD KNYDDDGITY 180
181 LFDLDMFDDA SEYTVDAQNY GDVSRFFNHS CSPNIAIYSA VRNHGFRTIY DLAFFAIKDI 240
241 QPLEELTFDY AGAKDFSPVQ SQKSQQNRIS KLRRQCKCGS ANCRGWLFG
|
| Detection Method: | |
| Confidence: | 62.522879 |
| Match: | 1mvhA |
| Description: | SET domain of Clr4 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| histone methyltransferase activity | 6.64131160914647 | bayes_pls_golite062009 |
| protein methyltransferase activity | 6.08778683840554 | bayes_pls_golite062009 |
| histone-lysine N-methyltransferase activity | 5.83932313719163 | bayes_pls_golite062009 |
| protein-lysine N-methyltransferase activity | 5.83932313719163 | bayes_pls_golite062009 |
| lysine N-methyltransferase activity | 5.83932313719163 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 5.55774492432055 | bayes_pls_golite062009 |
| N-methyltransferase activity | 3.98411678860954 | bayes_pls_golite062009 |
| S-adenosylmethionine-dependent methyltransferase activity | 2.69428385009711 | bayes_pls_golite062009 |
| methyltransferase activity | 2.33114816345072 | bayes_pls_golite062009 |
| binding | 2.2675356705139 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 2.25175257044903 | bayes_pls_golite062009 |
| nucleic acid binding | 2.20425750757954 | bayes_pls_golite062009 |
| chromatin binding | 1.26889182518944 | bayes_pls_golite062009 |
| protein binding | 0.938282161933492 | bayes_pls_golite062009 |
| transferase activity | 0.653108419761009 | bayes_pls_golite062009 |
| RNA binding | 0.589947603398124 | bayes_pls_golite062009 |
| catalytic activity | 0.414641636618101 | bayes_pls_golite062009 |
