YRC Public Data Repository - Protein Structure Prediction

Protein:	cce1
Organism:	Schizosaccharomyces pombe
Length:	258 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cce1.

Description	E-value	Query Range	Subject Range
gi\|39942308, gi\|... - gi\|39942308\|ref\|XP_360691.1\| hypothetical protein MGG_03234 [Magnaporthe grisea 70-15], gb\|EAA51639....	285.0	[0..5]	[242..18]
gi\|190409811 - gi\|190409811\|gb\|EDV13076.1\| cruciform cutting endonuclease [Saccharomyces cerevisiae RM11-1a] CCE1 - Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination... gi\|151941534 - gi\|151941534\|gb\|EDN59897.1\| cruciform cutting endonuclease [Saccharomyces cerevisiae YJM789] CCE1_YEAST - Cruciform cutting endonuclease 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2...	226.0	[0..42]	[250..69]
gi\|85079933 - gi\|85079933\|ref\|XP_956447.1\| hypothetical protein NCU03338 [Neurospora crassa OR74A] gi\|28917512, gi\|... - gi\|32403966\|ref\|XP_322596.1\| predicted protein [Neurospora crassa], gi\|28917512\|gb\|EAA27211.1\| predi...	199.0	[0..49]	[227..158]
gi\|49094226, gi\|... - gi\|67528478\|ref\|XP_662041.1\| hypothetical protein AN4437.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	180.0	[0..98]	[242..825]
orf19.10774, orf... - CCE1 CGDID:CAL0003364 Assembly 19, Contig19-10172 (114414, 113416) CDS, reverse complemented, transl... gi\|46439623, gi\|... - gi\|68476158\|ref\|XP_717888.1\| hypothetical protein CaO19.10774 [Candida albicans SC5314], gi\|68476027...	175.0	[0..43]	[237..66]
gi\|115398137, gi... - gi\|115398137\|ref\|XP_001214660.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	175.0	[0..1]	[242..14]
gi\|169773757 - gi\|169773757\|ref\|XP_001821347.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83769208 - gi\|83769208\|dbj\|BAE59345.1\| unnamed protein product [Aspergillus oryzae]	174.0	[0..1]	[241..14]
gi\|159124989 - gi\|159124989\|gb\|EDP50106.1\| conserved hypothetical protein [Aspergillus fumigatus A1163] gi\|70994640, gi\|... - gi\|70994640\|ref\|XP_752097.1\| conserved hypothetical protein [Aspergillus fumigatus Af293], gi\|668497...	148.0	[0..1]	[243..14]
gi\|49528320, gi\|... - gi\|50293191\|ref\|XP_449007.1\| unnamed protein product [Candida glabrata], gi\|49528320\|emb\|CAG61977.1\|... gi\|49528320 - gi\|49528320\|emb\|CAG61977.1\| unnamed protein product [Candida glabrata]	128.0	[0..1]	[251..11]
gi\|116199863, gi... - gi\|88179366\|gb\|EAQ86834.1\| hypothetical protein CHGG_08087 [Chaetomium globosum CBS 148.51], gi\|1161...	114.0	[0..9]	[150..77]

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Predicted Domain #1

Region A:
Residues: [1-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATVKLSFLQ HICKLTGLSR SGRKDELLRR IVDSPIYPTS RVLGIDLGIK NFSYCFASQN  60
   61 EDSKVIIHNW SVENLTEKNG LDIQWTEDFQ PSSMADLSIQ LFNTLHEKFN PHVILMERQR 120
  121 YRSGIATIPE WTLRVNMLES MLYALHYAEK RNSIEQKIQY PFLLSLSPKS TYSYWASVLN 180
  181 TKASFSKKKS RVQMVKELID GQKILFENEE ALYKWNNGSR VEFKKDDMAD SALIASGWMR 240
  241 WQAQLKHYRN FCKQFLKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	112.0
Match:	1kcfA
Description:	Mitochondrial resolvase ydc2 N-terminal domain; Mitochondrial resolvase ydc2 catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nuclease activity	2.26556994009539	bayes_pls_golite062009
exonuclease activity	2.2254764376369	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.75713164321634	bayes_pls_golite062009
hydrolase activity	1.52863974928789	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
ribonuclease activity	1.21758166782745	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1.19309748194103	bayes_pls_golite062009
deoxyribonuclease activity	1.1219517187744	bayes_pls_golite062009
binding	0.777766550398053	bayes_pls_golite062009
DNA polymerase activity	0.717600245625866	bayes_pls_golite062009
endonuclease activity	0.635517699603511	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.568273228950698	bayes_pls_golite062009
3'-5' exonuclease activity	0.4571735090405	bayes_pls_golite062009
transcription factor binding	0.39731466816166	bayes_pls_golite062009
transcription cofactor activity	0.32137240853612	bayes_pls_golite062009
exodeoxyribonuclease activity	0.278838342302102	bayes_pls_golite062009
small conjugating protein ligase activity	0.264176022241505	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.261428436029202	bayes_pls_golite062009
protein binding	0.242714557118293	bayes_pls_golite062009
SUMO ligase activity	0.17047695151047	bayes_pls_golite062009
nucleic acid binding	0.129994528216387	bayes_pls_golite062009
ligase activity	0.0697252959635399	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: