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View Structure Prediction Details

Protein: cdc5
Organism: Schizosaccharomyces pombe
Length: 757 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cdc5.

Description E-value Query
Range
Subject
Range
gi|40742885, gi|... - gi|67901016|ref|XP_680764.1| hypothetical protein AN7495.2 [Aspergillus nidulans FGSC A4], ref|XP_41...
565.0 [0..1] [751..1]
gi|73973038 - gi|73973038|ref|XP_532156.2| PREDICTED: similar to CDC5-like [Canis familiaris]
560.0 [0..1] [756..107]
gi|42554826, gi|... - gi|46136583|ref|XP_389983.1| hypothetical protein FG09807.1 [Gibberella zeae PH-1], gi|42554826|gb|E...
544.0 [0..1] [756..1]
gi|20521049 - gi|20521049|dbj|BAA24862.2| KIAA0432 [Homo sapiens]
541.0 [0..1] [756..26]
gi|50745288 - gi|50745288|ref|XP_420058.1| PREDICTED: similar to KIAA0432 [Gallus gallus]
534.0 [0..1] [752..87]
CDC5L_BOVIN - Cell division cycle 5-like protein OS=Bos taurus GN=CDC5L PE=2 SV=1
531.0 [0..1] [756..1]
gi|109071344 - gi|109071344|ref|XP_001100220.1| PREDICTED: similar to CDC5-like isoform 2 [Macaca mulatta]
531.0 [0..1] [756..1]
CEF1_EMENI - Pre-mRNA-splicing factor cef1 OS=Emericella nidulans GN=cef1 PE=3 SV=1
CEF1_EMENI - Pre-mRNA-splicing factor cef1 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRR...
531.0 [0..1] [751..1]
gi|50510485 - gi|50510485|dbj|BAD32228.1| mKIAA0432 protein [Mus musculus]
529.0 [0..1] [756..31]

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Predicted Domain #1
Region A:
Residues: [1-118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVLKGGAWK NTEDEILKAA VSKYGKNQWA RISSLLVRKT PKQCKARWYE WIDPSIKKTE  60
   61 WSREEDEKLL HLAKLLPTQW RTIAPIVGRT ATQCLERYQK LLDDLEAKEN EQLGLISG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
RNA binding 2.55617811004485 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 1.04132983826241 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.810065362108106 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [119-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGAEAAAPVN DPNSRLRFGE AEPNLETLPA LPDAIDMDED EKEMLSEARA RLANTQGKKA  60
   61 KRKDREKQLE LTRRLSHLQK RRELKAAGIN IKLFRRKKNE MDYNASIPFE KKPAIGFYDT 120
  121 SEEDRQNFRE KREADQKIIE NGIRNNEMES EGRKFGHFEK PKPIDRVKKP NKDAQEEKMR 180
  181 RLAEAEQMSK RRKLNLPSPT VSQDELDKVV KLGFAGDRAR AMTDTTPDAN YSTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.522879
Match: 2i1jA
Description: No description for 2i1jA was found.

Predicted Domain #3
Region A:
Residues: [353-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLGKYTQIER ATPLRTPISG ELEGREDSVT IEVRNQLMRN REQSSLLGQE SIPLQPGGTG  60
   61 YTGVTPSHAA NGSALAAP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [431-757]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QATPFRTPRD TFSINAAAER AGRLASEREN KIRLKALREL LAKLPKPKND YELMEPRFAD  60
   61 ETDVEATVGV LEEDATDRER RIQERIAEKE RLAKARRSQV IQRDLIRPSV TQPEKWKRSL 120
  121 ENEDPTANVL LKEMIALISS DAINYPFGNS KVKGTANKVP DLSNEEIERC RLLLKKEIGQ 180
  181 LESDDYIQFE KEFLETYSAL HNTSSLLPGL VIYEEDDEDV EAAEKFYTND IQRDLAKKAL 240
  241 ECNKLENRVY DLVRSSYEQR NFLIKKISHA WKALQTERKN LTCYEFLYNQ ERLALPNRLE 300
  301 AAEIELSKMQ QIEAYAQQDY ARVTGQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle