YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: pcm-PA
Organism: Drosophila melanogaster
Length: 1612 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pcm-PA.

Description E-value Query
Range
Subject
Range
gi|109048979 - gi|109048979|ref|XP_001112265.1| PREDICTED: similar to 5-3 exoribonuclease 1 isoform 1 [Macaca mulat...
1626.0 [0..1] [1577..1]

Back

Predicted Domain #1
Region A:
Residues: [1-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVPKFFRYI SERYPCLSEL AREHCIPEFD NLYLDMNGIV HNCSHPDDNN IHFHLEEEQI  60
   61 FQEIFNYVDK LFYLIKPQRL FFLSVDGVAP RAKMNQQRSR RFRTAREAEQ QEAKAAQRGE 120
  121 LREHERFDSN CITPGTEFMV RLQEGLRAFL KTKISTDPLW QRCTVILSGQ EAPGEGEHKI 180
  181 MDYIRYMKTQ PDYDPNTRHC LYGLDADLII LGLCTHELHF VVLREEVKFG RNVKRTSVEE 240
  241 TRFFLLHLGL LREYLELEFD ALRTDEHKLD IAQLIDDWVL MGFLVGNDFI PHLPCLHISS 300
  301 NALPLLYRTY IGIYPTLGGN INENGKLNLR RLQIFISALT EVELDHFKEH ADDLKYMNNK 360
  361 SEAFDMDVGE ITESQNLDSD LGALINKSML LYDDDSEEDC SDENAVLLKE FQNYKRNFYR 420
  421 NKFKRDPNDE LIEELCHHYV NALQWVLDYY Y

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.85
Match: 1ul1X
Description: Crystal structure of the human FEN1-PCNA complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endonuclease activity 2.45869331497094 bayes_pls_golite062009
hydrolase activity 2.24171130786956 bayes_pls_golite062009
binding 1.99360183638569 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.96755600188402 bayes_pls_golite062009
nucleic acid binding 1.68917463278047 bayes_pls_golite062009
DNA binding 1.63116261448437 bayes_pls_golite062009
nuclease activity 1.55313849436792 bayes_pls_golite062009
exonuclease activity 1.29727662049967 bayes_pls_golite062009
catalytic activity 1.27951740231695 bayes_pls_golite062009
endodeoxyribonuclease activity 1.12391156671522 bayes_pls_golite062009
deoxyribonuclease activity 1.11025090301954 bayes_pls_golite062009
ribonuclease activity 0.974421387546058 bayes_pls_golite062009
flap endonuclease activity 0.405877291452351 bayes_pls_golite062009
protein binding 0.388252010955945 bayes_pls_golite062009
5'-3' exonuclease activity 0.371408632109349 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.237820137780736 bayes_pls_golite062009
ribonuclease H activity 0.234391225960316 bayes_pls_golite062009
endoribonuclease activity 0.097472492148219 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [452-611]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RGVQSWDWYY PFHYTPFISD LKNIEQVEIA FHMGTPFLPF QQLLAVLPAA SAKLLPVAYH  60
   61 DLMLLPTSPL AEFYPLEFES DLNGKKHDWE AVVLIPFIDE GRLLAAMLPC EAQLSLEERE 120
  121 RNRHGPMYVY KYSTVAQGPM PAYPPLRALP VLYCTEVAKW 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [612-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SHEIAVNLPY SVCIELPNAA RTVFFPGFPT MQHLPFDFEL RNDRVKVFEQ VSRNQNIVLK  60
   61 PRKRQLEDTL TAVASQYLGK VIHVGWPHLV KAIVVRVATR DQRVDSEGIT LNDSRRFDSE 120
  121 CKALQEHFIN RMGIQFANYD VLVYVRTFAG NSTEFRDKGA LMVRDSWSSS VTGYPAQGVV 180
  181 ADLTVWERMR KNFLNVEHYF PVGSTIFLIT DPYYGSEGTV QDPRL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [837-1011]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYTNGRIQVS IMVRPEPKVN AARQLQEERD RDYLSTFQVC NLLRISGRTL GRLSGTVWVV  60
   61 LGPRRQKMEN VTKHNIGLQL KYPRQNEERA GYCFRTNNQW YYSSLAVDLM RNYCQRYPDV 120
  121 IDFFGDSNDR AEFVFEQDVF PNAVGHRRVE ELANWVRQQP HMKVERISCG SKTVC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1012-1612]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RETIELLIAA VDDLRSLPVK HVKLQVKPHL LIKPNVTLPD VYRSKRPVRL FDRVVIVRTI  60
   61 YMVPVGTKGT VIGIHPVTDP NPVRLECVHA VDTFCKVLFD SPVPNCNNIH GIAEDRVYKV 120
  121 PEIALVIIKT DEEGKKQNDC ELPVRDPQPN QAQDEPVRAT SSRYVTAAGS TSVPITMKTQ 180
  181 ISDEFVKTRS DPIARTDSYK PSSEPKPVPV PEQITNWRER VSTPTNKPQP APNNWRINRS 240
  241 SSRQQGGSIF VAPPTKTPDA AASTASTAFT AASSATLTPL DQTLALMSVL GVGEDQSSPP 300
  301 LQEAVQQQRP PLLQQQRAPF PGQMPNLPKP PLFWQQEAQK QEALQQEAQQ QEAQKKQQQA 360
  361 HAQMEPERIN SQHFYRSGQT GAALNQPPLG APSKRQWHEW VHPRMQHANA FHAGVNNGYQ 420
  421 MRPKKNIAAQ STFNNNVHMH LQQPYYPNQQ QQQQQQQPLQ LTEINNAPPR YSTIQDFVPI 480
  481 QAYRPKKLNR VQPAGRQDVD ATKNPSRSPV LQQPTNETID TKASSSLPVQ SAGEQVIGLM 540
  541 QTLEIKPAAS QSESDGVSTG SANAPTATTS SQAVNRRKHR VPRIGAKFDL EYILPDSPHP 600
  601 T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.39794
Match: 1y0fA
Description: No description for 1y0fA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle