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View Structure Prediction Details

Protein: FBpp0309323
Organism: Drosophila melanogaster
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309323.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
281.0 [0..61] [379..2532]

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Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYLYNASMH CEDEERVNFY NMDKFFVPHV QSIELEQQAI LRQYVPQYAY QWPWGFAPSA  60
   61 YSYYQGF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [68-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSLNMMTMDI TKTEPGLVGL SSNQQQQQQQ QSQQSNAGMN SGGQNNGPNP NGNGNVVNVV  60
   61 NSGGAGGGNN GNGNVQSIAA AANNNNNNNN NGSQLCAGCG KHIQDRYLLR AL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.522879
Match: 1meyC
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [180-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMLWHEDCLK CGCCDCRLGE VGSTLYTKGN LMLCKRDYLR LFGNTGYCAA CSKVIPAFEM  60
   61 VMRARTNVYH LECFACQQCN HRFCVGDRFY LCENKILC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 2dfyX
Description: No description for 2dfyX was found.

Predicted Domain #4
Region A:
Residues: [278-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYDYEERLVF ASMANHPMLK RHVSSLGQGS PTGAAGAQNT AGGLLGGGPG GGNVNGVGMV  60
   61 NGPRTPGDHN NNNNGPQTPT GGGSPFAAAA AAAAAAAHMK NQLGASS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 2cuqA
Description: Solution Structure of Second Lim Domain from Human Skeletal Muscle Lim-Protein 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
DNA binding 3.60745514727532 bayes_pls_golite062009
nucleic acid binding 3.47256374293954 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
transcription activator activity 2.9532663930699 bayes_pls_golite062009
transcription factor activity 2.90769972671972 bayes_pls_golite062009
sequence-specific DNA binding 2.72967350701574 bayes_pls_golite062009
protein binding 2.44501340584871 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.40923942043513 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.49515149729803 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.26452462867497 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.68943696300126 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
transcription repressor activity 0.256420113528322 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle