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View Structure Prediction Details

Protein: FBpp0309323
Organism: Drosophila melanogaster
Length: 384 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309323.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
281.0 [0..61] [379..2532]

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Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEYLYNASMH CEDEERVNFY NMDKFFVPHV QSIELEQQAI LRQYVPQYAY QWPWGFAPSA  60
   61 YSYYQGF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [68-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSLNMMTMDI TKTEPGLVGL SSNQQQQQQQ QSQQSNAGMN SGGQNNGPNP NGNGNVVNVV  60
   61 NSGGAGGGNN GNGNVQSIAA AANNNNNNNN NGSQLCAGCG KHIQDRYLLR AL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.522879
Match: 1meyC
Description: Designed zinc finger protein
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [180-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DMLWHEDCLK CGCCDCRLGE VGSTLYTKGN LMLCKRDYLR LFGNTGYCAA CSKVIPAFEM  60
   61 VMRARTNVYH LECFACQQCN HRFCVGDRFY LCENKILC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 2dfyX
Description: No description for 2dfyX was found.

Predicted Domain #4
Region A:
Residues: [278-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYDYEERLVF ASMANHPMLK RHVSSLGQGS PTGAAGAQNT AGGLLGGGPG GGNVNGVGMV  60
   61 NGPRTPGDHN NNNNGPQTPT GGGSPFAAAA AAAAAAAHMK NQLGASS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 2cuqA
Description: Solution Structure of Second Lim Domain from Human Skeletal Muscle Lim-Protein 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.00967542385368 bayes_pls_golite062009
DNA binding 3.60745514727532 bayes_pls_golite062009
nucleic acid binding 3.47256374293954 bayes_pls_golite062009
binding 2.96409924710655 bayes_pls_golite062009
transcription activator activity 2.9532663930699 bayes_pls_golite062009
transcription factor activity 2.90769972671972 bayes_pls_golite062009
sequence-specific DNA binding 2.72967350701574 bayes_pls_golite062009
protein binding 2.44501340584871 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.40923942043513 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.49515149729803 bayes_pls_golite062009
transcription factor binding 1.38523780690867 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.26452462867497 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.68943696300126 bayes_pls_golite062009
transcription cofactor activity 0.58115018700114 bayes_pls_golite062009
transcription repressor activity 0.256420113528322 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle