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View Structure Prediction Details

Protein: l(1)G0007-PA
Organism: Drosophila melanogaster
Length: 1222 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for l(1)G0007-PA.

Description E-value Query
Range
Subject
Range
gi|39644987, gi|... - gi|41053698|ref|NP_957170.1| DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Danio rerio], gi|39644987|gb...
779.0 [0..4] [1222..2]

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Predicted Domain #1
Region A:
Residues: [1-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDDDESGVH RLEGTAGQET RGGLVIRKPK DAGAGGGGGF KVPQGSMLGL DKLAAKRRAE  60
   61 KERSERLISF KDSEFDDTGG GSSTPQANAS GASSEFAFKK PDTKSFEKLR GQLREHKDDT 120
  121 PSHTGGVSEK ARERLREHIQ RDRKRGPVSS TAAEGRDRDR DWDRDRRRDR DRDRDRDRDR 180
  181 RQHRERERDR HRSWDRDRGR DRD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [204-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDRSMSERSV HTPREPGTPG GSSGGISNSS WDDEDGEFGQ RKSDWDMPTP RRHGNKSGDW  60
   61 SVRSGGSRRN HGRQDDTVRP TPAHRYNQWA HGRKRSGATP WGEDPESLDL WEEEQRRLDR 120
  121 EWYNIDEGYD DENNPFGGPN SEYFRKREEQ LEQKRTKRIS AQQRQNNRDN ELWERNRMLT 180
  181 SGVVTLISV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [393-515]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDDFDEEALE RVHLLVHHII PPFLDGRIVF TKQPEPVVPV KDPTSDMALL ARKGSALVRN  60
   61 YREQKERRKA QKKHWELSGT KLGNIMGVQR PQDEDDMRFD KEKDKADYRK DQKFADHMRD 120
  121 QDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.045757
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #4
Region A:
Residues: [516-1090]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGKSDFSRKK TISEQRRFLP VFASRQELLN VIRENSVIII VGETGSGKTT QLTQYLHEDG  60
   61 YSKRGMIGCT QPRRVAAMSV AKRVSDEMDT QLGEDVGYAI RFEDCTSERT VIKYMTDGIL 120
  121 LRESLRDPEL DSYSAIIMDE AHERSLSTDV LFGLLREIVA RRHDLKLIVT SATMDSSKFA 180
  181 TFFGNVPTFT IPGRTFPVDV MFSKNTCEDY VESAVKQALQ VHLTPNEGDM LIFMPGQEDI 240
  241 EVTCEVLEER LAEIDNAPAL SILPIYSQLP SDLQAKIFQK SSDGLRKCVV ATNIAETSLT 300
  301 VDGIIYVIDS GYCKLKVYNP RIGMDALQIY PISQANANQR SGRAGRTGPG QAYRLYTQRQ 360
  361 YKDELLALTV PEIQRTNLAN TVLLLKSLGV VDLLQFHFMD PPPQDNILNS LYQLWILGAL 420
  421 DHTGALTTLG RQMAEFPLDP PQCQMLIVAC RMGCSAEVLI IVSMLSVPSI FYRPKGREDE 480
  481 ADGVREKFQR PESDHLTYLN VYQQWRQNNY SSTWCNEHFI HIKAMRKVRE VRQQLKDIMT 540
  541 QQNLSVISCG IDWDIVRKCI CSAYFYQAAR LKGIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.09691
Match: 2p6rA
Description: No description for 2p6rA was found.

Predicted functions:

Term Confidence Notes
4.704140727858 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
structural constituent of ribosome 1.57653963868443 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
nucleic acid binding 1.41477043612798 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
DNA binding 1.11699929651302 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
transcription regulator activity 0.989226939888218 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
helicase activity 0.6191010101321 bayes_pls_golite062009
motor activity 0.61636596887462 bayes_pls_golite062009
structural molecule activity 0.596382945962261 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.461763181659193 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.458831409927227 bayes_pls_golite062009
pyrophosphatase activity 0.455976987338331 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.422944846459286 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
DNA insertion or deletion binding 0.36048959456844 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.338958888186454 bayes_pls_golite062009
purine NTP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
ATP-dependent helicase activity 0.29664013896754 bayes_pls_golite062009
translation release factor activity 0.178286731022211 bayes_pls_golite062009
translation termination factor activity 0.151456842619444 bayes_pls_golite062009
nucleotide binding 0.114848452385726 bayes_pls_golite062009
purine nucleotide binding 0.10713474095071 bayes_pls_golite062009
purine ribonucleotide binding 0.0916519414118148 bayes_pls_golite062009
ribonucleotide binding 0.0915913646217636 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
transcription factor activity 0.0434163635422169 bayes_pls_golite062009
cytoskeletal protein binding 0.0272673919333979 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [1091-1222]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYVNLRTGMP CHLHPTSALY GLGTTPDYVV YHELIMTAKE YMQCATAVDG YWLAELGPMF  60
   61 FSVKESGRSG REKKKQAAEH LKEMEEQMLK AQHEMEERKQ QAAEREEQLA TKQEIATPGN 120
  121 ATPRRTPARI GL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle