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View Structure Prediction Details

Protein: CG1847-PB
Organism: Drosophila melanogaster
Length: 331 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG1847-PB.

Description E-value Query
Range
Subject
Range
gi|68380124 - gi|68380124|ref|XP_688976.1| PREDICTED: similar to Aryl-hydrocarbon interacting protein-like 1 [Dani...
210.0 [0..1] [331..406]

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Predicted Domain #1
Region A:
Residues: [1-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSRSKSDMK PIRKEILNPG NAYIELTPGT RRLTPHDIGL FQVKFHFQTR RAGDSRIIDD  60
   61 SRKMEKPMEL VLGKKFKLEV WELIVQQMSL NEVAKFTVHK SLCAQYPFIS KTLRDIGKKP 120
  121 EERRHCCGMT LQNEGIGYTD LDELLQNPSD LEFIIELFSI ELPEQYEKER WQMSDDEKML 180
  181 ATSTLRERGN NFYKASRFTE AETCYREAVG IVEQLMLKEK PHDEEWQELA AIKTPLLLNY 240
  241 AQCRLIAGDF YAVIEHCNEV LTLDPRNVKA LFRRAKAHAG AWNPAQARRD FLDALALDAS 300
  301 LKSTVSKELK SIEDQQQARN VQDRIHMQKL F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 32.0
Match: 1qz2A
Description: Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidyl-prolyl cis-trans isomerase activity 4.0615867467963 bayes_pls_golite062009
cis-trans isomerase activity 3.99265212272703 bayes_pls_golite062009
intracellular ligand-gated calcium channel activity 3.76779231976671 bayes_pls_golite062009
ryanodine-sensitive calcium-release channel activity 3.76779231976671 bayes_pls_golite062009
calcium-release channel activity 3.5823026493473 bayes_pls_golite062009
transcription regulator activity 2.39036685719765 bayes_pls_golite062009
isomerase activity 2.31710030777753 bayes_pls_golite062009
macrolide binding 1.71427500929512 bayes_pls_golite062009
binding 1.63170667962375 bayes_pls_golite062009
FK506 binding 1.49236065710546 bayes_pls_golite062009
drug binding 1.28204013795445 bayes_pls_golite062009
catalytic activity 0.885282592863018 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.327099943267853 bayes_pls_golite062009
transferase activity 0.31967318602798 bayes_pls_golite062009
kinase activity 0.301313235341922 bayes_pls_golite062009
unfolded protein binding 0.27473817613726 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.225873481281805 bayes_pls_golite062009
transcription elongation regulator activity 0.13387993108257 bayes_pls_golite062009
protein kinase activity 0.102400286544695 bayes_pls_golite062009
protein binding 0.0371998661994551 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle