Protein: | Hex-A-PA |
Organism: | Drosophila melanogaster |
Length: | 541 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Hex-A-PA.
Description | E-value | Query Range |
Subject Range |
|
649.0 | [0..1] | [541..1] |
Region A: Residues: [1-541] |
1 11 21 31 41 51 | | | | | | 1 MDRELNGAMK SVSINSAQLN GHNNGGGLDE TDRVGVAQGA ALSATEKITT TTAAATKSAT 60 61 ATTNATTATA TTTNLTTHSP QQIALLSAAE KSKMVHELCQ QLLLTDEQVQ ELCYRILHEL 120 121 RRGLAKDTHP KANVKCFVTY VQDLPNGNER GKFLALDLGG TNFRVLLIHL QENNDFQMES 180 181 RIYAIPQHIM IGSGTQLFDH IAECLSNFMA EHNVYKERLP LGFTFSFPLR QLGLTKGLLE 240 241 TWTKGFNCAG VVNEDVVQLL KDAIARRGDV QIDVCAILND TTGTLMSCAW KNHNCKIGLI 300 301 VGTGANACYM ERVEEAELFA AEDPRKKHVL INTEWGAFGD NGALDFVRTE FDRDIDVHSI 360 361 NPGKQTFEKM ISGMYMGELV RLVLVKMTQA GILFNGQDSE VLNTRGLFFT KYVSEIEADE 420 421 PGNFTNCRLV LEELGLTNAT DGDCANVRYI CECVSKRAAH LVSAGIATLI NKMDEPTVTV 480 481 GVDGSVYRFH PKFHNLMVEK ISQLIKPGIT FDLMLSEDGS GRGAALVAAV ACREDILNGK 540 541 K |
Detection Method: | ![]() |
Confidence: | 174.0 |
Match: | 1czaN |
Description: | Mammalian type I hexokinase |
Matching Structure (courtesy of the PDB):![]() |
Term | Confidence | Notes |
kinase activity | 2.81480196738665 | bayes_pls_golite062009 |
phosphotransferase activity, alcohol group as acceptor | 2.66634930184926 | bayes_pls_golite062009 |
transferase activity, transferring phosphorus-containing groups | 2.47806699612578 | bayes_pls_golite062009 |
carbohydrate kinase activity | 2.33338276303563 | bayes_pls_golite062009 |
binding | 2.11855816699924 | bayes_pls_golite062009 |
transcription regulator activity | 2.09111975841662 | bayes_pls_golite062009 |
protein binding | 2.00711904074672 | bayes_pls_golite062009 |
nucleic acid binding | 1.84294882554466 | bayes_pls_golite062009 |
hexokinase activity | 1.70516840340504 | bayes_pls_golite062009 |
DNA binding | 1.70014394990425 | bayes_pls_golite062009 |
cytoskeletal protein binding | 1.69431775343358 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 1.58791290104307 | bayes_pls_golite062009 |
glucose binding | 1.58717365638543 | bayes_pls_golite062009 |
transferase activity | 1.58048472128722 | bayes_pls_golite062009 |
transcription activator activity | 1.35676801272576 | bayes_pls_golite062009 |
hydrolase activity, acting on acid anhydrides | 1.30214785132007 | bayes_pls_golite062009 |
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 1.30181101672725 | bayes_pls_golite062009 |
pyrophosphatase activity | 1.27871475799533 | bayes_pls_golite062009 |
myosin binding | 1.26046360733002 | bayes_pls_golite062009 |
nucleoside-triphosphatase activity | 1.18894708772738 | bayes_pls_golite062009 |
transcription factor activity | 1.06678984888387 | bayes_pls_golite062009 |
structural molecule activity | 0.998075030492697 | bayes_pls_golite062009 |
general RNA polymerase II transcription factor activity | 0.908385694796738 | bayes_pls_golite062009 |
mannokinase activity | 0.766256764215041 | bayes_pls_golite062009 |
actin binding | 0.742062735414161 | bayes_pls_golite062009 |
protein kinase activity | 0.659672620542945 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 0.574998559133169 | bayes_pls_golite062009 |
hydrolase activity | 0.474893704700898 | bayes_pls_golite062009 |
glucokinase activity | 0.47468456642723 | bayes_pls_golite062009 |
sugar binding | 0.44352406324938 | bayes_pls_golite062009 |
adenyl nucleotide binding | 0.426216374317549 | bayes_pls_golite062009 |
ATP binding | 0.39408967688855 | bayes_pls_golite062009 |
adenyl ribonucleotide binding | 0.358452809509562 | bayes_pls_golite062009 |
ATPase activity | 0.338933039062396 | bayes_pls_golite062009 |
catalytic activity | 0.296484721581333 | bayes_pls_golite062009 |
monosaccharide binding | 0.20435276425198 | bayes_pls_golite062009 |
purine nucleotide binding | 0.173637392484485 | bayes_pls_golite062009 |
nucleotide binding | 0.168207023557983 | bayes_pls_golite062009 |
ribonucleotide binding | 0.104339549630743 | bayes_pls_golite062009 |
purine ribonucleotide binding | 0.101742118226005 | bayes_pls_golite062009 |
chromatin binding | 0.0489277194984092 | bayes_pls_golite062009 |