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View Structure Prediction Details

Protein: otu-PC, otu-PB
Organism: Drosophila melanogaster
Length: 853 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for otu-PC, otu-PB.

Description E-value Query
Range
Subject
Range
gi|9743652 - gi|9743652|gb|AAF97987.1| ovarian tumor protein isoform [Drosophila melanogaster]
619.0 [0..1] [853..1]

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Predicted Domain #1
Region A:
Residues: [1-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMQVQRPIT SGSRQAPDPY DQYLESRGLY RKHTARDASS LFRVIAEQMY DTQMLHYEIR  60
   61 LECVRFMTLK RRIFEKEIPG DFDSYMQDMS KPKTYGTMTE LRAMSCLYRR NVILYEPYNM 120
  121 GTSVVFNRRY AENFRVFFNN ENHFDSVYDV EYIERAAICQ SIAFKLLYQK LFKLPDVSFA 180
  181 VEIMLHPHTF NWDRFNVEFD DKGYMVRIHC TDGRVFKLDL PGDTNCILEN 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.3
Match: 1tffA
Description: Structure of Otubain-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.88517380556644 bayes_pls_golite062009
binding 1.28926196684576 bayes_pls_golite062009
catalytic activity 0.995453662223124 bayes_pls_golite062009
nucleic acid binding 0.896894355256917 bayes_pls_golite062009
transcription regulator activity 0.864586149211676 bayes_pls_golite062009
DNA binding 0.816807038934629 bayes_pls_golite062009
cysteine-type peptidase activity 0.549530710974169 bayes_pls_golite062009
peptidase activity 0.302979577950347 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.292810452153222 bayes_pls_golite062009
transcription activator activity 0.188306014444124 bayes_pls_golite062009
transcription factor activity 0.0522574655989047 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [231-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKLCNFHSTN GNQSINARKG GRLEIKNQEE RKASGSSGHE PNDLLPMCPN RLESCVRQLL  60
   61 DDGISPFPYK VAKSMDPYMY RNIEFDCWND MRKEAKLYNV YINDYNFKVG AKCKVELPNE 120
  121 TEMYTCHVQN ISKDKNYCHV FVERIGKEIV VPYESLH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [388-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPPDEYRPW SLPFRYHRQM PRLPLPKYAG KANKSSKWKK NKLFEMDQYF EHSKCDLMPY  60
   61 MPVDNCYQGV HIQDDEQRDH NDPEQNDQNP TTEQRDREEP QAQKQHQRTK ASRVQPQNSS 120
  121 SSQNQEVSGS AAPPPTQYMN YVPMIPSRPG HLPPPWPASP MAIAEEFPFP ISGTPHPPPT 180
  181 EGCVYMPFGG YGPPPPGAVA LSGPHPFMPL PSPP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [602-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNVTGIGEPR RSLHPNGEDL PVDMVTLRYF YNMGVDLHWR MSHHTPPDEL GMFGYHQQNN  60
   61 TDQQAGRTVV IGATEDNLTA VESTPPPSPE VANATEQSPL EKSAYAKRNL NSVKVRGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [720-853]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPEQLQDIKD SLGPAAFLPT PTPSPSSNGS QFSFYTTPSP HHHLITPPRL LQPPPPPPIF  60
   61 YHKAGPPQLG GAAQGQTPYA WGMPAPVVSP YEVINNYNMD PSAQPQQQQP ATLQPAPLSV 120
  121 QSQPAAVYAA TRHH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle