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View Structure Prediction Details

Protein: otu-PC, otu-PB
Organism: Drosophila melanogaster
Length: 853 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for otu-PC, otu-PB.

Description E-value Query
Range
Subject
Range
gi|9743652 - gi|9743652|gb|AAF97987.1| ovarian tumor protein isoform [Drosophila melanogaster]
619.0 [0..1] [853..1]

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Predicted Domain #1
Region A:
Residues: [1-230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMQVQRPIT SGSRQAPDPY DQYLESRGLY RKHTARDASS LFRVIAEQMY DTQMLHYEIR  60
   61 LECVRFMTLK RRIFEKEIPG DFDSYMQDMS KPKTYGTMTE LRAMSCLYRR NVILYEPYNM 120
  121 GTSVVFNRRY AENFRVFFNN ENHFDSVYDV EYIERAAICQ SIAFKLLYQK LFKLPDVSFA 180
  181 VEIMLHPHTF NWDRFNVEFD DKGYMVRIHC TDGRVFKLDL PGDTNCILEN 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.3
Match: 1tffA
Description: Structure of Otubain-2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein binding 1.88517380556644 bayes_pls_golite062009
binding 1.28926196684576 bayes_pls_golite062009
catalytic activity 0.995453662223124 bayes_pls_golite062009
nucleic acid binding 0.896894355256917 bayes_pls_golite062009
transcription regulator activity 0.864586149211676 bayes_pls_golite062009
DNA binding 0.816807038934629 bayes_pls_golite062009
cysteine-type peptidase activity 0.549530710974169 bayes_pls_golite062009
peptidase activity 0.302979577950347 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.292810452153222 bayes_pls_golite062009
transcription activator activity 0.188306014444124 bayes_pls_golite062009
transcription factor activity 0.0522574655989047 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [231-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKLCNFHSTN GNQSINARKG GRLEIKNQEE RKASGSSGHE PNDLLPMCPN RLESCVRQLL  60
   61 DDGISPFPYK VAKSMDPYMY RNIEFDCWND MRKEAKLYNV YINDYNFKVG AKCKVELPNE 120
  121 TEMYTCHVQN ISKDKNYCHV FVERIGKEIV VPYESLH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [388-601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPPDEYRPW SLPFRYHRQM PRLPLPKYAG KANKSSKWKK NKLFEMDQYF EHSKCDLMPY  60
   61 MPVDNCYQGV HIQDDEQRDH NDPEQNDQNP TTEQRDREEP QAQKQHQRTK ASRVQPQNSS 120
  121 SSQNQEVSGS AAPPPTQYMN YVPMIPSRPG HLPPPWPASP MAIAEEFPFP ISGTPHPPPT 180
  181 EGCVYMPFGG YGPPPPGAVA LSGPHPFMPL PSPP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [602-719]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNVTGIGEPR RSLHPNGEDL PVDMVTLRYF YNMGVDLHWR MSHHTPPDEL GMFGYHQQNN  60
   61 TDQQAGRTVV IGATEDNLTA VESTPPPSPE VANATEQSPL EKSAYAKRNL NSVKVRGK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [720-853]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPEQLQDIKD SLGPAAFLPT PTPSPSSNGS QFSFYTTPSP HHHLITPPRL LQPPPPPPIF  60
   61 YHKAGPPQLG GAAQGQTPYA WGMPAPVVSP YEVINNYNMD PSAQPQQQQP ATLQPAPLSV 120
  121 QSQPAAVYAA TRHH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle