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View Structure Prediction Details

Protein: Cbp80-PA, Cbp80-PB
Organism: Drosophila melanogaster
Length: 800 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Cbp80-PA, Cbp80-PB.

Description E-value Query
Range
Subject
Range
gi|114625872 - gi|114625872|ref|XP_520138.2| PREDICTED: nuclear cap binding protein subunit 1, 80kDa [Pan troglodyt...
1139.0 [0..1] [800..122]

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Predicted Domain #1
Region A:
Residues: [1-800]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRRRAHDTE DEGYDHRRNK RRRVSENQEI EDRLESLILR VGERSTSSVE SNLEGLVSVL  60
   61 EADLGTFRLK ILRILSDCAV RMPEKCTVYT TLVGLLNAKN YKFGGEFVDH MVKTFKESLK 120
  121 MCRWDAARYS LRFLADLVNC HVISATSLLQ LLDTMIDVSN EDTVPQVRRD WFVFAVLSTL 180
  181 PWVGRDLYEK KESALESLLL RIEVYLNKRS KKHHNALRVW SSDAPHPQEE YLDCLWAQIR 240
  241 KLRQDNWAEK HIPRPYLVFD SILCEALQHN LPTIVPPPHH DNFEYPMPWV VYRMFDYTDC 300
  301 PDGPNLPGAH SIERFLIEEH LHHIIETYHH ERKDCAAQLL SFPYKHKIPL EYCIVEVVFA 360
  361 ELFHMPTPRY LDICYGSILI ELCKLQPATL PQVLAQATEI LFMRIDSMNT SCFDRFVNWF 420
  421 SYHLSNFKFT WSWDEWDSCL LLDGEHPRPK FIQEVLQKCL RLSYHQRITE MMPTTYAKLI 480
  481 PLTPVPNYKY ANEEAANLPG TTVAHQLVVA IRQKCTPEEV VNILKDIPNS GYSGEEMSDG 540
  541 SFNALKIDVF VQTLLNLGSK SFSHSFAAIS KFHSVFRALA ETEEAQICIL HNIFELWSSH 600
  601 QQMMVVLIDK LLKLQIVDCS AVATWIFSKE MTGEFTKLYL WEILHLTIKK MNKHVIKLNT 660
  661 ELSEAKEKLA KADSSSSDSE DDSSHKRKKP ITHADKPSEE VVERMEEKLE AANVNQKRLF 720
  721 LIVFQRFIMI LSEHLLRSDT DGRDPDTDWY RWTIGRLQQV FLMHHEQVQK YSSTLETLLF 780
  781 TSDLDTHILE VFQQFVALRA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1n52A
Description: CBP80, 80KDa nuclear cap-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA cap binding 6.31996430626206 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
protein binding 2.78733902345842 bayes_pls_golite062009
nucleic acid binding 2.74745843355294 bayes_pls_golite062009
RNA binding 2.62683106046883 bayes_pls_golite062009
transcription regulator activity 1.90912542848632 bayes_pls_golite062009
DNA binding 1.77040152722002 bayes_pls_golite062009
transcription activator activity 1.33885628961586 bayes_pls_golite062009
transcription factor activity 1.27944481949335 bayes_pls_golite062009
mRNA binding 1.24616647164637 bayes_pls_golite062009
RNA 7-methylguanosine cap binding 0.841392474686331 bayes_pls_golite062009
transcription factor binding 0.00210118982863072 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle