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View Structure Prediction Details

Protein: dnc-PN
Organism: Drosophila melanogaster
Length: 983 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnc-PN.

Description E-value Query
Range
Subject
Range
dnc-PG - The gene dunce is referred to in FlyBase by the symbol Dmel\dnc (CG32498, FBgn0000479). It is a prot...
849.0 [0..170] [983..1]

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Predicted Domain #1
Region A:
Residues: [1-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIATLFIIFA FIRAFPWSRK RGRPALALTL MPEGGEDHRG DLNQKGENNN RPRPSISLAN  60
   61 NGEAMAPRTR RKSSKFHEVT FSGSVGGGDS DGGGEAINGG NLDVSPSKRH SLSTTTSNSS 120
  121 SAPYRYLSGS SRSRGSRGDC HEYYQLQQHS SSLSNGNRGN RGLSQRSDTM ATEAEGEEFD 180
  181 VD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [183-430]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMDEDDEDQT YDRETEEFYS NIQDAAGTGS SSRSKRSSLF SRSDSSATTT SSSGGGTFTG  60
   61 GKRRSAASIL SSSMCSDLMT SDRRSSTATE YSVKSVTTGN TSQRRSSGRI RRYVSRMTIA 120
  121 GARRRTTGSF DVENGQGARS PLEGGSPSAG LVLQNLPQRR ESFLYRSDSD FEMSPKSMSR 180
  181 NSSIASESHG EDLIVTPFAQ ILASLRSVRN NLLSLTNVPA SNKSRRPNQS SSASRSGNPP 240
  241 GAPLSQGE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [431-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAYTRLATDT IEELDWCLDQ LETIQTHRSV SDMASLKFKR MLNKELSHFS ESSRSGNQIS  60
   61 EYICSTFLDK QQEFDLPSLR VEDNPELVAA NAAAGQQSAG QYARSRSPRG PPMSQISGVK 120
  121 RPLSHTNS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [559-983]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTGERLPTFG VETPRENELG TLLGELDTWG IQIFSIGEFS VNRPLTCVAY TIFQSRELLT  60
   61 SLMIPPKTFL NFMSTLEDHY VKDNPFHNSL HAADVTQSTN VLLNTPALEG VFTPLEVGGA 120
  121 LFAACIHDVD HPGLTNQFLV NSSSELALMY NDESVLENHH LAVAFKLLQN QGCDIFCNMQ 180
  181 KKQRQTLRKM VIDIVLSTDM SKHMSLLADL KTMVETKKVA GSGVLLLDNY TDRIQVLENL 240
  241 VHCADLSNPT KPLPLYKRWV ALLMEEFFLQ GDKERESGMD ISPMCDRHNA TIEKSQVGFI 300
  301 DYIVHPLWET WADLVHPDAQ DILDTLEENR DYYQSMIPPS PPPSGVDENP QEDRIRFQVT 360
  361 LEESDQENLA ELEEGDESGG ESTTTGTTGT TAASALSGAG GGGGGGGGMA PRTGGCQNQP 420
  421 QHGGM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 141.0
Match: 2fm0A
Description: No description for 2fm0A was found.

Predicted functions:

Term Confidence Notes
cyclic-nucleotide phosphodiesterase activity 3.86434485322172 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 3.8566356686502 bayes_pls_golite062009
phosphoric diester hydrolase activity 3.16734214417311 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 2.29938697204184 bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity 2.29281173183086 bayes_pls_golite062009
catalytic activity 1.44092158711463 bayes_pls_golite062009
hydrolase activity 1.06080266556153 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.815214868148798 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.196287846714023 bayes_pls_golite062009
binding 0.0840884387362641 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle