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View Structure Prediction Details

Protein: dnc-PI, dnc-PJ
Organism: Drosophila melanogaster
Length: 1070 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dnc-PI, dnc-PJ.

Description E-value Query
Range
Subject
Range
dnc-PD - The gene dunce is referred to in FlyBase by the symbol Dmel\dnc (CG32498, FBgn0000479). It is a prot...
1077.0 [0..1] [1070..1]

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Predicted Domain #1
Region A:
Residues: [1-45]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQESNGGPA AGGGAAAAPP PPPQYIITTP SEVDPDEVRS MADLE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [46-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSPEKQVQV QSQKFSSTSS TTKVATHSFS MSSSAGTTGQ QSKQDSAQQI QQLQQLQQLQ  60
   61 QLQQQQQQQQ SQRIISSSTR SQSLQSSTIV GEATTITSGA AQILSASAAA SLAQQLKAQS 120
  121 STSIITSSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [175-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRTSTSTSSS SSTRYIASGS SNLAGGNSNS ASSASSKTRF QSFLQQPEGA HGFLTAHQKH  60
   61 VRQFVRSTSA HSEAAAGVAG ARAEKCIRSA STQIDDASVA GVVESAGNLT DSSATGGSMQ 120
  121 LSMSKLGLQQ SSSILISKSA ETIEMKSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [323-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAGMRTQLTL SGGFLAPPGN RKITILSPIH APPGLHDMLK RAQGRSPLSP RISFPGSDSD  60
   61 LFGFDVENGQ GARSPLEGGS PSAGLVLQNL PQRRESFLYR SDSDFEMSPK SMSRNSSIAS 120
  121 ERFKEQEASI LVDRSHGEDL IVTPFAQILA SLRSVRNNLL SLTNVPASNK SRRPNQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [499-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSASRSGNP PGAPLSQGEE AYTRLATDTI EELDWCLDQL ETIQTHRSVS DMASLKFKRM  60
   61 LNKELSHFSE SSRSGNQISE YICSTFLDKQ 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [589-1070]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEFDLPSLRV EDNPELVAAN AAAGQQSAGQ YARSRSPRGP PMSQISGVKR PLSHTNSFTG  60
   61 ERLPTFGVET PRENELGTLL GELDTWGIQI FSIGEFSVNR PLTCVAYTIF QSRELLTSLM 120
  121 IPPKTFLNFM STLEDHYVKD NPFHNSLHAA DVTQSTNVLL NTPALEGVFT PLEVGGALFA 180
  181 ACIHDVDHPG LTNQFLVNSS SELALMYNDE SVLENHHLAV AFKLLQNQGC DIFCNMQKKQ 240
  241 RQTLRKMVID IVLSTDMSKH MSLLADLKTM VETKKVAGSG VLLLDNYTDR IQVLENLVHC 300
  301 ADLSNPTKPL PLYKRWVALL MEEFFLQGDK ERESGMDISP MCDRHNATIE KSQVGFIDYI 360
  361 VHPLWETWAD LVHPDAQDIL DTLEENRDYY QSMIPPSPPP SGVDENPQED RIRFQVTLEE 420
  421 SDQENLAELE EGDESGGEST TTGTTGTTAA SALSGAGGGG GGGGGMAPRT GGCQNQPQHG 480
  481 GM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.0
Match: 2fm0A
Description: No description for 2fm0A was found.

Predicted functions:

Term Confidence Notes
cyclic-nucleotide phosphodiesterase activity 4.70762025272187 bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity 4.66767157264894 bayes_pls_golite062009
phosphoric diester hydrolase activity 4.40961779134517 bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity 3.68838886134169 bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity 2.64567538445993 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.26293733853576 bayes_pls_golite062009
hydrolase activity 1.17086565360856 bayes_pls_golite062009
catalytic activity 1.07048165010262 bayes_pls_golite062009
binding 0.994379083280533 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.893957699588543 bayes_pls_golite062009
protein binding 0.162314119157812 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle