






| Protein: | Ptx1-PA |
| Organism: | Drosophila melanogaster |
| Length: | 509 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ptx1-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
134.0 | [0..1] | [509..1] |
|
Region A: Residues: [1-193] |
1 11 21 31 41 51
| | | | | |
1 MDRSSAVGGC GGGGGLGVGV VTSSATALGP GGLTNGGGGV VSGALNGLEA MSAESTGLCL 60
61 QDLVSAGTAN GAGSAGSAES ATTTSTALSS GSTGSSTVNG GGSSTSGTEH LHSHHSLHDS 120
121 SSSVSISPAI SSLMPISSLS HLHHSAGQDL VGGYSQHPHH TVVPPHTPKH EPLEKLRIWA 180
181 ETGDFRDSHS SMT
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [194-258] |
1 11 21 31 41 51
| | | | | |
1 AVANSLDSTH LNNFQTSSTS SISNRSRDRK DGNRSVNETT IKTENISSSG HDEPMTTSGE 60
61 EPKND
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [259-327] |
1 11 21 31 41 51
| | | | | |
1 KKNKRQRRQR THFTSQQLQE LEHTFSRNRY PDMSTREEIA MWTNLTEARV RVWFKNRRAK 60
61 WRKRERNAM
|
| Detection Method: | |
| Confidence: | 15.045757 |
| Match: | 1yz8P |
| Description: | Solution structure of the k50 class homeodomain pitx2 bound to dna and implications for mutations that cause rieger syndrome |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.20953772435302 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.26183812259792 | bayes_pls_golite062009 |
| transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
| transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.14886080629275 | bayes_pls_golite062009 |
| chromatin binding | 0.876241359231159 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| protein binding | 0.830419844171551 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.663171909351326 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
| transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
|
Region A: Residues: [328-509] |
1 11 21 31 41 51
| | | | | |
1 NAAVAAADFK SGFGTQFMQP FADDSLYSSY PYNNWTKVPS PLGTKPFPWP VNPLGSMVAG 60
61 NHHQNSVNCF NTGASGVAVS MNNASMLPGS MGSSLSNTSN VGAVGAPCPY TTPANPYMYR 120
121 SAAEPCMSSS MSSSIATLRL KAKQHASAGF GSPYSAPSPV SRSNSAGLSA CQYTGVGVTD 180
181 VV
|
| Detection Method: | |
| Confidence: | 1.37 |
| Match: | 1pk8A |
| Description: | Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP |
Matching Structure (courtesy of the PDB):![]() |
|