Protein: | Ptx1-PA |
Organism: | Drosophila melanogaster |
Length: | 509 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Ptx1-PA.
Description | E-value | Query Range |
Subject Range |
|
134.0 | [0..1] | [509..1] |
Region A: Residues: [1-193] |
1 11 21 31 41 51 | | | | | | 1 MDRSSAVGGC GGGGGLGVGV VTSSATALGP GGLTNGGGGV VSGALNGLEA MSAESTGLCL 60 61 QDLVSAGTAN GAGSAGSAES ATTTSTALSS GSTGSSTVNG GGSSTSGTEH LHSHHSLHDS 120 121 SSSVSISPAI SSLMPISSLS HLHHSAGQDL VGGYSQHPHH TVVPPHTPKH EPLEKLRIWA 180 181 ETGDFRDSHS SMT |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [194-258] |
1 11 21 31 41 51 | | | | | | 1 AVANSLDSTH LNNFQTSSTS SISNRSRDRK DGNRSVNETT IKTENISSSG HDEPMTTSGE 60 61 EPKND |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
Region A: Residues: [259-327] |
1 11 21 31 41 51 | | | | | | 1 KKNKRQRRQR THFTSQQLQE LEHTFSRNRY PDMSTREEIA MWTNLTEARV RVWFKNRRAK 60 61 WRKRERNAM |
Detection Method: | ![]() |
Confidence: | 15.045757 |
Match: | 1yz8P |
Description: | Solution structure of the k50 class homeodomain pitx2 bound to dna and implications for mutations that cause rieger syndrome |
Matching Structure (courtesy of the PDB):![]() |
Term | Confidence | Notes |
transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
nucleic acid binding | 4.20953772435302 | bayes_pls_golite062009 |
transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
binding | 3.02779747447702 | bayes_pls_golite062009 |
sequence-specific DNA binding | 2.41271657675151 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 2.26183812259792 | bayes_pls_golite062009 |
transcription repressor activity | 1.91962622287073 | bayes_pls_golite062009 |
transcription activator activity | 1.77700860354597 | bayes_pls_golite062009 |
transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
specific RNA polymerase II transcription factor activity | 1.14886080629275 | bayes_pls_golite062009 |
chromatin binding | 0.876241359231159 | bayes_pls_golite062009 |
transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
protein binding | 0.830419844171551 | bayes_pls_golite062009 |
general RNA polymerase II transcription factor activity | 0.663171909351326 | bayes_pls_golite062009 |
transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
transcription corepressor activity | 0.25931464844298 | bayes_pls_golite062009 |
Region A: Residues: [328-509] |
1 11 21 31 41 51 | | | | | | 1 NAAVAAADFK SGFGTQFMQP FADDSLYSSY PYNNWTKVPS PLGTKPFPWP VNPLGSMVAG 60 61 NHHQNSVNCF NTGASGVAVS MNNASMLPGS MGSSLSNTSN VGAVGAPCPY TTPANPYMYR 120 121 SAAEPCMSSS MSSSIATLRL KAKQHASAGF GSPYSAPSPV SRSNSAGLSA CQYTGVGVTD 180 181 VV |
Detection Method: | ![]() |
Confidence: | 1.37 |
Match: | 1pk8A |
Description: | Crystal Structure of Rat Synapsin I C Domain Complexed to Ca.ATP |
Matching Structure (courtesy of the PDB):![]() |