| Protein: | Fur1-PB |
| Organism: | Drosophila melanogaster |
| Length: | 1269 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fur1-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
732.0 | [0..1] | [923..1] |
|
Region A: Residues: [1-226] |
1 11 21 31 41 51
| | | | | |
1 MKNDVVRWSR QPTSNTTNSS SSSRSDSNST HKHRSKSNKL NARQLGSNAA RSCQQRSSVA 60
61 TTLEDEQQTI IECDIGNFNF DCNLFKTSFL TQHKQKRSGK SSSKSKSNRS RPLAKTKAVF 120
121 LLALQFSAVV FLCNINVGFV AGSVATAASS AGGSSPAAPS SAPSSPPTVA VPPPPPPSSA 180
181 LKVDPNGQSP VLPPYVLDYE TGGKAKLTPN NGKFGQSGSS GSNNNH
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [227-712] |
1 11 21 31 41 51
| | | | | |
1 IVGHYTHTWA VHIPNGDNGM ADAVAKDHGF VNLGKIFDDH YHFAHHKVSK RSLSPATHHQ 60
61 TRLDDDDRVH WAKQQRAKSR SKRDFIRMRP SRTSSRAMSM VDAMSFNDSK WPQMWYLNRG 120
121 GGLDMNVIPA WKMGITGKGV VVTILDDGLE SDHPDIQDNY DPKASYDVNS HDDDPMPHYD 180
181 MTDSNRHGTR CAGEVAATAN NSFCAVGIAY GASVGGVRML DGDVTDAVEA RSLSLNPQHI 240
241 DIYSASWGPD DDGKTVDGPG ELASRAFIEG TTKGRGGKGS IFIWASGNGG REQDNCNCDG 300
301 YTNSIWTLSI SSATEEGHVP WYSEKCSSTL ATTYSSGGQG EKQVVTTDLH HSCTVSHTGT 360
361 SASAPLAAGI AALVLQSNQN LTWRDLQHIV VRTAKPANLK DPSWSRNGVG RRVSHSFGYG 420
421 LMDAAEMVRV ARNWKAVPEQ QRCEINAPHV DKVIPPRTHI TLQLTVNHCR SVNYLEHVQA 480
481 KITLTS
|
| Detection Method: | |
| Confidence: | 77.0 |
| Match: | 1r6vA |
| Description: | Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nerve growth factor binding | 5.17216805931457 | bayes_pls_golite062009 |
| peptidase activity | 4.77677490610016 | bayes_pls_golite062009 |
| neurotrophin binding | 4.47215080222714 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 4.40501322467328 | bayes_pls_golite062009 |
| serine hydrolase activity | 4.30899317351154 | bayes_pls_golite062009 |
| serine-type peptidase activity | 4.29545891350519 | bayes_pls_golite062009 |
| endopeptidase activity | 3.83336601331518 | bayes_pls_golite062009 |
| serine-type endopeptidase activity | 3.71508033196614 | bayes_pls_golite062009 |
| hydrolase activity | 2.1123944590511 | bayes_pls_golite062009 |
| eukaryotic cell surface binding | 1.50287724152407 | bayes_pls_golite062009 |
| binding | 1.08901362883653 | bayes_pls_golite062009 |
| catalytic activity | 0.597535457699629 | bayes_pls_golite062009 |
| exopeptidase activity | 0.42083764849682 | bayes_pls_golite062009 |
| protein binding | 0.380935140681308 | bayes_pls_golite062009 |
| receptor binding | 0.222369968782666 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.11649614154172 | bayes_pls_golite062009 |
|
Region A: Residues: [713-806] |
1 11 21 31 41 51
| | | | | |
1 QRRGDIQLFL RSPANTSVTL LTPRIHDNSR SGFNQWPFMS VHTWGESPQG NWQLEIHNEG 60
61 RYMGHALLRE WSLIFYGTTQ SIGPNDPISV PKPS
|
| Detection Method: | |
| Confidence: | 2.05 |
| Match: | 1p8jA |
| Description: | Furin, C-terminal domain; Furin, N-terminal domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [807-895] |
1 11 21 31 41 51
| | | | | |
1 GSEATTPNSS STTSNLHQAY SPQYPRIPPN NFGSSPSGGS KLPLGKVPPP NKSSYVTNNP 60
61 LLNSAPPKQG YQQISATYGV ILGKANGKS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [896-1269] |
1 11 21 31 41 51
| | | | | |
1 NNNSKEKTNN KGNKSNNGNK GKSGGSSGNR KEQTTQSTII QTSTSKNKYY RISQQQQQKN 60
61 NKQDRNGVQT QRPKANSGEK SYDEKSRKVV GEITTNSGNG SIKAAKQVKE STTTSSNSRI 120
121 PKLFERYEKI QAIFPELEPY ENSSPKGKPK QAKQGKQFEV DLFKPTNGGN SRQGNTKKSP 180
181 SVPPPSQTMA TLSILPILPA GGSSFLPDQK ILKKQQLLMA AAGVMAPAQV EVEMEEVHAT 240
241 PDYEARKDQR KEVNGPNAQI TQWDMIFYGT ETPAQPDDVA NPSQSNQFNL YGNDMAHNDV 300
301 EYDSTGQWRN MQQVGEVGMT RDHSNTAACL KWSDRKCLGL SLLFFMIMQV FFLNFKHAND 360
361 NNNKNKNNII KCIR
|
| Detection Method: | |
| Confidence: | 3.154902 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
