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View Structure Prediction Details

Protein: dan-PA, FBpp0303321
Organism: Drosophila melanogaster
Length: 678 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dan-PA, FBpp0303321.

Description E-value Query
Range
Subject
Range
DAN_DROPS - Protein distal antenna OS=Drosophila pseudoobscura pseudoobscura GN=dan PE=3 SV=1
gi|54640417, gi|... - gi|54640417|gb|EAL29347.1| GA11234-PA [Drosophila pseudoobscura], gi|126002551|ref|XP_001352378.1| G...
226.0 [0..1] [678..1]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIRMGTKGK RPLRSLTPRD KIHAIQRIHD GESKASVARD IGVPESTLRG WCKNEDKLRF  60
   61 MSRQSATDNL CADALGDKMD GGGGGGGGAG GGGLLGPPEK RQRLDGALPL NFSNKLKFDE 120
  121 LAFKRSPLNG LDYSTNKNLA DLGYNGLPVD YAAFNGGVKA KVFGADINRP AADP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.11
Match: 1hlvA
Description: DNA-binding domain of centromere binding protein B (CENP-B)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.86538715425734 bayes_pls_golite062009
DNA binding 4.40186699787632 bayes_pls_golite062009
nucleic acid binding 3.98153794570167 bayes_pls_golite062009
transcription factor activity 3.78935192723648 bayes_pls_golite062009
binding 2.92574888336072 bayes_pls_golite062009
sequence-specific DNA binding 2.15328641013602 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.00875399167309 bayes_pls_golite062009
transcription repressor activity 1.69615348178304 bayes_pls_golite062009
transcription activator activity 1.5973137667873 bayes_pls_golite062009
transcription factor binding 1.24678737091956 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.865913662624162 bayes_pls_golite062009
protein binding 0.795494287543952 bayes_pls_golite062009
transcription cofactor activity 0.691780246385357 bayes_pls_golite062009
chromatin binding 0.65622150362507 bayes_pls_golite062009
transcription corepressor activity 0.0723215858239072 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [175-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLNAISPLSS LTHLSGLTGI SQSPLAISFN ELTTNLNLLA QLNPGLAAMS GLNSFPAGAG  60
   61 NLRTPKPSGQ TPLQVQSPRS DSGDRSAQGL SVKNWAKQKP GEGQGSLNLS IKNEGKGGDI 120
  121 KSPSPSIAPS QMGGPMTLSN LAEDPLLYWL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [325-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSQQTMLGLN PLYPPTIPMG VTSPPIRSST PQHMSQLAQT PPIPSAPLTP SSTPSGSLDE  60
   61 KNAAWYNWCK AFGASLHTLN PNAATLAALQ ANQLQQQVAT TAAEGGSMGD PSNILYSHLT 120
  121 KETETPSVRS LSSNEQNPEA DEATETDLDG EVEPEASGKP EDLSAAGKVM TPSQSPIAHS 180
  181 SGSRSPEPKA KTKTPETTNS TSECKKILDN MLFKMGGMEA TGPLMPEQGS SESEGSFQDT 240
  241 SNPHTNNNDV SAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [578-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNNNNNNSNK TDEEEKAKYL DCTADEDIEA IRHGEKFLQW LENCSNPRVT AVQLMQLRFL  60
   61 IAAIKSGNET PMIEKSALPE DSEEHAAEEE GSGRGKSRRR K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle