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View Structure Prediction Details

Protein: danr-PA
Organism: Drosophila melanogaster
Length: 419 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for danr-PA.

Description E-value Query
Range
Subject
Range
DANR_DROPS - Protein distal antenna-related OS=Drosophila pseudoobscura pseudoobscura GN=danr PE=3 SV=1
gi|54640419, gi|... - gi|54640419|gb|EAL29349.1| GA12437-PA [Drosophila pseudoobscura], gi|126002556|ref|XP_001352380.1| G...
218.0 [0..1] [417..1]

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Predicted Domain #1
Region A:
Residues: [1-141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDISAYQHMN IRMSTRGKRP LRNLTPNDKV RAIQRIHNGE TKASVSRDIG VPESTLRGWC  60
   61 KNEQKLRFMC RQLGPDHLGL DTPPEKRAKF ELQLQLPPKF VALPPNYEEL GFGALPYSPA 120
  121 DYPVQNESLL EKLSLVEFVK K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.522879
Match: 1hlvA
Description: DNA-binding domain of centromere binding protein B (CENP-B)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.20953772435302 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.26183812259792 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.14886080629275 bayes_pls_golite062009
chromatin binding 0.876241359231159 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [142-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGGLHPEGAL HPGQAGVMDY SNNMLHQLNL LALLNSKLTP QTADVLVDAQ PKSEDNKVID  60
   61 SPAASEDYSK NNYPLLSVKN WAKDPAKRVN SANQPEQVND KNNNALEANS SAPQALVTEQ 120
  121 AK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [264-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPMFSDTTMP LLPAPFPNPA DLAPVIAPVT PANAPPTGTD NQGAALLDWC KLFNASLNFL  60
   61 AFAAAAASMQ PGGGGPGGPS YNPNQMASGG SEPDLETYPF NEALLKRLSP LAHSEASNES 120
  121 YCDSEPEDLS VRSCASKASS RSHTPDKSVG SSDAEQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle