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View Structure Prediction Details

Protein: CG31121-PB, CG31...
Organism: Drosophila melanogaster
Length: 911 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG31121-PB, CG31....

Description E-value Query
Range
Subject
Range
gi|19528405 - gi|19528405|gb|AAL90317.1| RE11181p [Drosophila melanogaster]
607.0 [0..1] [911..1]

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Predicted Domain #1
Region A:
Residues: [1-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELSNFSSGK KMSREERRYS VPHGPNTPLP PAASEDLHAW SIYRQNLNSD FTDSALGSSD  60
   61 KSPLPYGNFQ LRDTTVQSIL NHPRYGPKSP LGSNMYTYLK FGLPRVFPPN AGSQRSHRPG 120
  121 PGPGAGPGHG HGGSSALGGV RGRVNRAFRD SSGAPAGAGS SGYDSSDN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [169-299]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETTRSRVPPN LRKYRSESDF RAIGGMPHSR PESRAQIGGG GVPMAALRQA NSRASIAVGQ  60
   61 HHHQMQQHQQ QYGKHYGHRS HSEADLLGAG LSQVDGGGGG MGYDYNEARL YGSSRQYGNG 120
  121 NGHNPGSRKQ S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [300-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GMGLIYPNIQ VHCLDVNPCL RGVSMQAKAG DLFAIMATSQ REGSALAECL AGLTERLGGE  60
   61 ILINGQQVSR RGLRELCSYV PALEVSSLDP RMSVQCTLNF HAALRGPIDR SDLEERMDVL 120
  121 IEDLGLNTVR ASNVSTLTHS EKQRLSVACQ LLAQSSLLIL DQVTSNMDIF DTFFLVEYLR 180
  181 QWCSGGRIVI MTLQPPTFEI LSMCSGVLLL SGGRTVFSGS RADLPRHMGE LGYPCPPFKN 240
  241 PADYYLDLVT LDDLSAAAML ESSARIESLA NAWDQINSEP PLAAPPASL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 71.69897
Match: 1q1bA
Description: Crystal structure of E. coli MalK in the nucleotide-free form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
P-P-bond-hydrolysis-driven transmembrane transporter activity 6.58863529263644 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 6.58067278719409 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 6.57974651657836 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 6.57922174989907 bayes_pls_golite062009
primary active transmembrane transporter activity 6.57807080367604 bayes_pls_golite062009
nucleoside-triphosphatase activity 6.48406410175216 bayes_pls_golite062009
active transmembrane transporter activity 6.48154954364331 bayes_pls_golite062009
pyrophosphatase activity 6.40467109535527 bayes_pls_golite062009
ATPase activity, coupled 6.40151534181487 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 6.38373914253885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 6.38247436082206 bayes_pls_golite062009
ATPase activity 6.30019941712404 bayes_pls_golite062009
hydrolase activity 4.60957912556603 bayes_pls_golite062009
purine ribonucleotide binding 3.40690615950081 bayes_pls_golite062009
ribonucleotide binding 3.40594996232845 bayes_pls_golite062009
purine nucleotide binding 3.3669118613715 bayes_pls_golite062009
nucleotide binding 3.33248266870364 bayes_pls_golite062009
ATP binding 3.17398570826788 bayes_pls_golite062009
adenyl ribonucleotide binding 3.12628113185041 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
adenyl nucleotide binding 3.0710107594224 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
binding 1.55526868300981 bayes_pls_golite062009
peptide-transporting ATPase activity 1.37783759788533 bayes_pls_golite062009
peptide transporter activity 1.19353064661766 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
catalytic activity 0.458437698837681 bayes_pls_golite062009
transmembrane receptor activity 0.243618208880507 bayes_pls_golite062009
receptor activity 0.236855932650268 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
motor activity 0.0492636236578701 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [589-911]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNFTMKAGFF GQISALIKRF AGYKQPGSLL TWISKLIAAA VLSLFIGCIF WDVPASDPQL  60
   61 SYHDRLGYHH CVMVLVYWPL VMLTIRDTQE DRRHAERDIR LGLYTRSLYI IVQSLLGLFP 120
  121 SLCIWLAYLL PAHSMAGLYT YSNSSDTGIY LYMGYMLLYL TLIQTLALFC AHLLPCKVSA 180
  181 SIVNGLISLA VAAVGGYLVH PQNLAQFWSW LQFVSPERWL LPVLVQDEYS AETLSNSAGL 240
  241 QLCRNKQVQH QEIIVQQPCP PPNGTQVLVD FELLPQQHVL DPTPTYDQTT SVALVLGSVL 300
  301 VFCVTFIVFL CNCRGACRRK RSR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle