YRC Public Data Repository - Protein Structure Prediction

Protein:	TFAM-PA
Organism:	Drosophila melanogaster
Length:	257 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFAM-PA.

Description	E-value	Query Range	Subject Range
gi\|109511369, gi... - gi\|109514150\|ref\|XP_001067329.1\| PREDICTED: similar to High mobility group protein 4 (HMG-4) (High m...	167.0	[0..55]	[241..375]
gi\|76609479 - gi\|76609479\|ref\|XP_610926.2\| PREDICTED: similar to high-mobility group box 3 [Bos taurus]	150.0	[0..55]	[254..364]
gi\|114596859 - gi\|114596859\|ref\|XP_517538.2\| PREDICTED: similar to HMGB2 protein [Pan troglodytes]	147.0	[0..38]	[249..162]
gi\|91080287 - gi\|91080287\|ref\|XP_973934.1\| PREDICTED: similar to High mobility group protein DSP1 (Dorsal switch p...	147.0	[0..39]	[225..683]
gi\|109076196 - gi\|109076196\|ref\|XP_001085665.1\| PREDICTED: similar to high-mobility group box 2 [Macaca mulatta]	136.0	[0..43]	[249..115]
AGAP000005-PA - high mobility group protein B1\|protein_coding\|X:32478:38479:-1\|gene:AGAP000005 gi\|55243831, gi\|... - gi\|58381316\|ref\|XP_311155.2\| ENSANGP00000019772 [Anopheles gambiae str. PEST], gi\|55243831\|gb\|EAA064...	134.0	[0..33]	[227..201]
gi\|94383594 - gi\|94383594\|ref\|XP_001052174.1\| PREDICTED: high mobility group box 2 [Mus musculus]	132.0	[0..44]	[249..78]

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Predicted Domain #1

Region A:
Residues: [1-257]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIYTTTLMSS RGGLIGSLIN KVRPLAAASI SNTPAVPSKT LEEQLGLPPR PKKPLTPYFR  60
   61 FMREQRPKLK AANPQITTVE VVRQLSKNWS DADAQLKERL QAEFKRDQQI YVEERTKYDA 120
  121 TLTEEQRAEI KQLKQDLVDA KERRQLRKRV KELGRPKKPA SAFLRFIASE RINTPQGDKQ 180
  181 TYREWHQKTT AKWTRLSDSE KEVYMQESRK EMELYRKAIS VWEEKMIRLG HIDVVRHGNL 240
  241 IDPPEPKPRK TLASKDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.69897
Match:	2gzkA
Description:	No description for 2gzkA was found.

Predicted functions:

Term	Confidence	Notes
DNA binding	4.56243042026586	bayes_pls_golite062009
nucleic acid binding	4.42927972796404	bayes_pls_golite062009
transcription regulator activity	4.36244161599487	bayes_pls_golite062009
sequence-specific DNA binding	3.55724742149483	bayes_pls_golite062009
transcription factor activity	3.28411755496908	bayes_pls_golite062009
binding	3.1918149935012	bayes_pls_golite062009
transcription activator activity	2.44785103043103	bayes_pls_golite062009
protein binding	2.18211240370246	bayes_pls_golite062009
transcription factor binding	1.46324768909727	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.34004089271327	bayes_pls_golite062009
chromatin binding	1.323916832561	bayes_pls_golite062009
transcription repressor activity	1.04044219600834	bayes_pls_golite062009
DNA bending activity	0.41929067872099	bayes_pls_golite062009
structure-specific DNA binding	0.32807045001653	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: