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View Structure Prediction Details

Protein: SF1-PA
Organism: Drosophila melanogaster
Length: 787 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SF1-PA.

Description E-value Query
Range
Subject
Range
gi|46110397, gi|... - gi|46110397|ref|XP_382256.1| hypothetical protein FG02080.1 [Gibberella zeae PH-1], gi|42546868|gb|E...
392.0 [0..208] [713..1126]

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Predicted Domain #1
Region A:
Residues: [1-236]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATPPDLLS LAASREVSAA VAVAASANGG SGRSADKERS RSRDRGRDKD KDRDKDRKKR  60
   61 DKDSRDRDSR RRDDRGDRDR DRERDRDSRS HRSKSRNYDD GDRRRKRSRS RDRDRDRKRD 120
  121 RDRDSRSRRS SSRGGRDDYD RSRRRRSRSR SYERRRNDRG SQRDQRDQHS QRSSRERTHV 180
  181 NPFDTSNSRN SLNQDHDQSR IPSLFDRQQG LETIREEGRE QRFDLTQTIQ ELMGNA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [237-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGNKGFASFF NSQNSNDSTS NGAFDNSADS AAERKRKRKS RWGGSENDKT FIPGMPTILP  60
   61 STLDPAQQEA YLVQFQIEEI SRKLRTGDLG ITQNPEERSP SP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [339-510]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPIYSSDGKR LNTREFRYRK RLEEQRHQLI VKMQTVNPEF KPPADYKPPV TRVSDKVLIP  60
   61 QEQHPDINFV GLLIGPRGNT LKAMEKDTGA KIIIRGKGSV KEGKVGRKDG QPLPGEDEPL 120
  121 HAFITAPNPE AVRKAVDKIK DVIRQGIEVP EGHNDLRRMQ LRELAQLNGT LR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.30103
Match: 1k1gA
Description: RNA splicing factor 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleic acid binding 4.28581120742478 bayes_pls_golite062009
RNA binding 4.07234389285213 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
mRNA binding 2.74771386314615 bayes_pls_golite062009
protein binding 2.21586499514642 bayes_pls_golite062009
transcription regulator activity 2.01194399592256 bayes_pls_golite062009
DNA binding 1.78469836520678 bayes_pls_golite062009
transcription factor activity 0.866815968834173 bayes_pls_golite062009
0.649281624091344 bayes_pls_golite062009
structure-specific DNA binding 0.64468203163713 bayes_pls_golite062009
transcription repressor activity 0.594072241231183 bayes_pls_golite062009
single-stranded DNA binding 0.28490151670131 bayes_pls_golite062009
transcription activator activity 0.210494225017032 bayes_pls_golite062009
transcription factor binding 0.139588254197875 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [511-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENDIQRCTCG STDHKSWQCP DKPIITNTIV CTSCGGTGHL TKDCRNKRPG SGVPGMACED  60
   61 SQAKIDEEYM SLMAELGEGP PPPSASAKTD PPASNGPQLH RASYSIFDKK PSQMQAIQSP 120
  121 PSSSSRDHQR DLGGWGAAAH EHGMGMEHGM GLDQHGHGLA AMDHGMSLGM EHAMAAYVPA 180
  181 PPGTQAPPPM PPPLMPWMSA PQPPPPATEP LNPPIPGTLP PLIPPPPGTS APPMPPWGGG 240
  241 AYSGWGGGYA PPPPPPCAPP PPALSLSQPP PPPPPSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1y0fB
Description: No description for 1y0fB was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle