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View Structure Prediction Details

Protein: GATAe-PA
Organism: Drosophila melanogaster
Length: 746 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GATAe-PA.

Description E-value Query
Range
Subject
Range
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
246.0 [0..5] [745..1151]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCKTISPSV NMQLKMEQQT TQQQQQQQQQ QQQQQQLQQQ QHQALTKQQL QLLDKIKLES  60
   61 SNGADQLAQQ TANNLDEQQE QQQQHQQQAA TSVGVVVQTG QAGVSEPEEQ YVVVPRNQRR 120
  121 ILTTAGTLEL NEARE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEPSTNASNA SSGSASDSHI EYQRSAHQSP GATHYVQMAP RNAEVTEQVG AAAGAPPGTI  60
   61 FAYPIICNGD DVAAIKIETL EKGEATGESQ QQQQQLQQHQ HQQQQQCPTP NGASYGETIV 120
  121 ISSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEALQHHHQQ QQQHQQQQHQ QQHHQHQAAA AASAAAQTVH IATSSHGGTV RFVTEDVRFT  60
   61 TAGPETSASN MYYDVPVVDG SVHANESKTY ADLGNAYAPF 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [360-530]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSSSFSSNS YAATLQQGNT IYSVPGTGQF LAKSESGLNQ TGLLRQTGPA TFQTISFEGG  60
   61 NGIEPLWASP APPEYQSVQF SNFHPQVIDE YGSGNMSTSH WPPASSIGQY DGSLVTASST 120
  121 SSPNHELKCE NCHGPFLRKG SEYFCPNCPA FMRMAPRITQ RQAKPKAAAA P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [531-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNRRNGVTCA NCQTNSTTLW RRNNEGNPVC NACGLYYKLH NMNRPLSMKK EGIQKRKRKP  60
   61 KNNGGAPMHR APLPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.09691
Match: 2gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.52732993750126 bayes_pls_golite062009
transcription regulator activity 1.70015379754395 bayes_pls_golite062009
DNA binding 1.65515523003574 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.50367193346192 bayes_pls_golite062009
protein binding 1.41749048987708 bayes_pls_golite062009
nucleic acid binding 1.36224073182023 bayes_pls_golite062009
transcription factor activity 1.14669021380366 bayes_pls_golite062009
sequence-specific DNA binding 1.0340476173844 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.701499822197 bayes_pls_golite062009
transcription activator activity 0.6614529953701 bayes_pls_golite062009
transcription factor binding 0.20735798780397 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.10722537662857 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [606-746]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGVNLMAN SPLYPSQVPV SMLNSQLNSQ QNSSPELHDM STTGQAGGQR VVSISLNATA  60
   61 PPTPDGTLNM SARHHVTGES HSPYSQQSTP QSQSPHLPGT VPINRQIVQP VPTIESSRSS 120
  121 NTELTPSVIT RTGLPERSSN N

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle