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View Structure Prediction Details

Protein: GATAe-PA
Organism: Drosophila melanogaster
Length: 746 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GATAe-PA.

Description E-value Query
Range
Subject
Range
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
246.0 [0..5] [745..1151]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCKTISPSV NMQLKMEQQT TQQQQQQQQQ QQQQQQLQQQ QHQALTKQQL QLLDKIKLES  60
   61 SNGADQLAQQ TANNLDEQQE QQQQHQQQAA TSVGVVVQTG QAGVSEPEEQ YVVVPRNQRR 120
  121 ILTTAGTLEL NEARE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEPSTNASNA SSGSASDSHI EYQRSAHQSP GATHYVQMAP RNAEVTEQVG AAAGAPPGTI  60
   61 FAYPIICNGD DVAAIKIETL EKGEATGESQ QQQQQLQQHQ HQQQQQCPTP NGASYGETIV 120
  121 ISSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [260-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEALQHHHQQ QQQHQQQQHQ QQHHQHQAAA AASAAAQTVH IATSSHGGTV RFVTEDVRFT  60
   61 TAGPETSASN MYYDVPVVDG SVHANESKTY ADLGNAYAPF 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [360-530]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSSSFSSNS YAATLQQGNT IYSVPGTGQF LAKSESGLNQ TGLLRQTGPA TFQTISFEGG  60
   61 NGIEPLWASP APPEYQSVQF SNFHPQVIDE YGSGNMSTSH WPPASSIGQY DGSLVTASST 120
  121 SSPNHELKCE NCHGPFLRKG SEYFCPNCPA FMRMAPRITQ RQAKPKAAAA P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [531-605]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNRRNGVTCA NCQTNSTTLW RRNNEGNPVC NACGLYYKLH NMNRPLSMKK EGIQKRKRKP  60
   61 KNNGGAPMHR APLPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.09691
Match: 2gatA
Description: Erythroid transcription factor GATA-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.52732993750126 bayes_pls_golite062009
transcription regulator activity 1.70015379754395 bayes_pls_golite062009
DNA binding 1.65515523003574 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.50367193346192 bayes_pls_golite062009
protein binding 1.41749048987708 bayes_pls_golite062009
nucleic acid binding 1.36224073182023 bayes_pls_golite062009
transcription factor activity 1.14669021380366 bayes_pls_golite062009
sequence-specific DNA binding 1.0340476173844 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.701499822197 bayes_pls_golite062009
transcription activator activity 0.6614529953701 bayes_pls_golite062009
transcription factor binding 0.20735798780397 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.10722537662857 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [606-746]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQGVNLMAN SPLYPSQVPV SMLNSQLNSQ QNSSPELHDM STTGQAGGQR VVSISLNATA  60
   61 PPTPDGTLNM SARHHVTGES HSPYSQQSTP QSQSPHLPGT VPINRQIVQP VPTIESSRSS 120
  121 NTELTPSVIT RTGLPERSSN N

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle