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View Structure Prediction Details

Protein: FBpp0082058
Organism: Drosophila melanogaster
Length: 2016 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0082058.

Description E-value Query
Range
Subject
Range
gi|39592304, gi|... - gi|39592304|emb|CAE75525.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae], gi|187020927|em...
gi|157762282 - gi|157762282|ref|XP_001673483.1| Hypothetical protein CBG23547 [Caenorhabditis briggsae AF16]
612.0 [0..11] [1968..84]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSVFTEAP SARPAAAEAD SNLVVVYSKS GISFDERAIG NIMEEKSIST ISVVRITSPT  60
   61 PSMVDQEEDE RLEELANFME TATDSELDSD NGSQSGGDNA SEMDEHDEEN HNTGDDNNSD 120
  121 STETEADAPR TRKRVGRKPK AIKKRKRRKP KERPQIVGLR VEQFYADNTA DMVVKNALKL 180
  181 AGVSVYKRTA ETDALMEVIR NDHNYTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [208-362]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTSPEQLKNH KRDEKMAMEM QAQSRKIIMQ APGSVKLINA KKRVQAIPLS PVQVKVQRLP  60
   61 VKPHQVQQAA QLQPKVQLIR KPIHSPLPRQ KPEIIANNSV NARLRPTRAP VKVIAPPVQE 120
  121 YIEDDDDAQS SDSAEEENAD KAYDSEEMSE ESDEF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [363-460]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QESDNDRDSD MDFDMRHSNR RNPNKRKRVR KVVRQTPSKP MKPLPPPPTT PQHFPELKKR  60
   61 KEVLEPKAPQ IGQIIQMPAT KSVPAVFALG RGLPSTSF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [461-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKIRPTHQSL PVKRPPLPTT PANSNVRRMP AVQLGRIVNS PQEVKEIIIN KNMASPKGVF  60
   61 TNLNTLLGED NNAATKSSPV PLRHRAVMSP STPRSSYNQQ MSPIVVPVPA QAHTPSKGFM 120
  121 PIGVDTAQSH KLPAQIVIET HQSSSELAAE NDKQLDLINS IVQDELLKST LVEQPVVNAD 180
  181 EDIPKLVKML ESTAADLDPP PVSLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [666-900]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNIFPAPEMQ GVGNAAAADP NNIMDTANED EITADFLQHV VGLIEEDKQF EAEVVKQVLA  60
   61 STEPGTLDAI VSMPTSIEPV DVPQAHTNLL PNASLTEPAQ SMTSLPIACS TPSRSVAAST 120
  121 PPTSAKVVRG YGRVIYLPPI EAPTTRAKRR AQFPSAPGMA ATSSSDAGNL SFGESSLDAS 180
  181 INQPLNTSSL SNDSQPGSGP KRPNPREPSM ARRSTAPRRS KKLDASQNND PDASE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [901-1040]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQEDDDDPNK LWCICRQPHN NRFMICCDLC EDWFHGTCVG VTKAMGTDME NKGIDWKCPK  60
   61 CVKRQEERSQ PRITDMLVTR PTTQPEQRPS ETKVLTTTAE IVQVAAPSAP RRTLPVVLTV 120
  121 ASSPMRIPMA KPAKKFPTGA 

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.12
Match: 1wemA
Description: Solution structure of PHD domain in death inducer-obliterator 1(DIO-1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.84543733401722 bayes_pls_golite062009
binding 2.84147289283175 bayes_pls_golite062009
DNA binding 2.61461572393763 bayes_pls_golite062009
nucleic acid binding 2.28792441212246 bayes_pls_golite062009
transcription factor activity 1.59046392323038 bayes_pls_golite062009
protein binding 1.32925779020231 bayes_pls_golite062009
transcription activator activity 0.663225694514289 bayes_pls_golite062009
transcription repressor activity 0.424927150874777 bayes_pls_golite062009
chromatin binding 0.0738512588250226 bayes_pls_golite062009
sequence-specific DNA binding 0.0471610688739243 bayes_pls_golite062009
histone binding 0.0304481539733681 bayes_pls_golite062009
transcription factor binding 0.0293954104210474 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [1041-1263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISHQQQQQLN FIRLGPSPGK RISETLCVVC KRPASTSSVY CGEECIRKYA QSAIQAHAAT  60
   61 KGPLPQNAGA QSLLNNSFDA KKNKKKDLFE DVLRQADTVS KVERINVFER KSGRVITGHM 120
  121 APSAHQFRKW LQENPSFEVL PSGTVQSADA EKRLLKGAPE AATSTSEPAV LGVAKKPPEG 180
  181 PAKLSHPQNT TVQASHQLGI SSVRPLAKKD KEKTTPTVQA PTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1264-1407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRIAAGKPEP VRIGIRRSLR EQLLARIKEA QAAEENSGQP TTQWPTVLEV DQFVKNVELE  60
   61 MFNSFGRDVG AKYKAKYRSL MFNIKDRKNR TLFEKICAKQ VEPRQLVRMT PEQLASQELA 120
  121 KWREEENRHQ LDMIKKSELD LLAC

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.23
Match: 2dmeA
Description: No description for 2dmeA was found.

Predicted Domain #9
Region A:
Residues: [1408-1558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQNYVVKTHK GEEVIATKVD VTLPEENVSE ASSMADTKQT SLVSEPSTST LERSTSREKA  60
   61 GSSKEKRHKS HKHHHRKRSR SRSNSRGRSV DKRHRRQHNE GGEQPGSGER EHRSREKQSR 120
  121 ERDEIVPSPL PKKRDENDQS PVPKKTAEKK T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1559-1705]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EASAYNLVDQ ILESEKTVEQ AANLGKPKPS PKPLPTLPSS LKAPEPMDNY SRYLHGLTTS  60
   61 SLWSGTLKMI DLADFEIVMY PVQGNCHQLG NLMPSQMDVI GRITRVNVWE YIKKLKKSPT 120
  121 KEVVIVNIFP ASPSETYKFD LFFEYLD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1706-1839]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRQRLGVLGV DSDQIRDFYI FPLGSGDKLP PALQTAEPVP FYEEAQRPNT LLGIIVRCLS  60
   61 KRPADAVPST PSVPTPVPAL SSKVAKRSRS SISYPAQSSP KRKISTHSTS SKDDEFDIDA 120
  121 IIKAPIAKLQ KTAP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1840-2016]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVVPQPSVPN DADEPYSPGG SDDELVPSAP QRPNDLERQV NEINKQIAAQ QMEIAGLLKV  60
   61 EPTGSASSSN VLAAISIPAN LSKILASIKD KTNLPSSADD GDEEYNPEDD ITATSSFASK 120
  121 KPRSKGRLAH LSEAELLSMV PDNLAGVIPR SSRTRHQLAQ SPLTPTPLPP PPPPPGV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle