| Protein: | hth-PB |
| Organism: | Drosophila melanogaster |
| Length: | 471 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hth-PB.
| Description | E-value | Query Range |
Subject Range |
|
|
393.0 | [0..1] | [471..1] |
|
Region A: Residues: [1-85] |
1 11 21 31 41 51
| | | | | |
1 MAQPRYDDGL HGYGMDSGAA AAAMYDPHAG HRPPGLQGLP SHHSPHMTHA AAAAATVGMH 60
61 GYHSGAGGHG TPSHVSPVGN HLMGA
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [86-243] |
1 11 21 31 41 51
| | | | | |
1 IPEVHKRDKD AIYEHPLFPL LALIFEKCEL ATCTPREPGV QGGDVCSSES FNEDIAMFSK 60
61 QIRSQKPYYT ADPEVDSLMV QAIQVLRFHL LELEKVHELC DNFCHRYISC LKGKMPIDLV 120
121 IDERDTTKPP ELGSANGEGR SNADSTSHTD GASTPDVR
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [244-342] |
1 11 21 31 41 51
| | | | | |
1 PPSSSLSYGG AMNDDARSPG AGSTPGPLSQ QPPALDTSDP GRWCRREWSS PADARNADAS 60
61 RRLYSSVFLG SPDNFGTSAS GDASNASIGS GEGTGEEDD
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [343-471] |
1 11 21 31 41 51
| | | | | |
1 DASGKKNQKK RGIFPKVATN ILRAWLFQHL THPYPSEDQK KQLAQDTGLT ILQVNNWFIN 60
61 ARRRIVQPMI DQSNRAVYTP HPGPSGYGHD AMGYMMDSQA HMMHRPPGDP GFHQGYPHYP 120
121 PAEYYGQHL
|
| Detection Method: | |
| Confidence: | 11.69897 |
| Match: | 1x2nA |
| Description: | Solution structure of the homeobox domain of human homeobox protein PKNOX1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 5.13863038737912 | bayes_pls_golite062009 |
| DNA binding | 4.66369707598026 | bayes_pls_golite062009 |
| nucleic acid binding | 4.51452285155271 | bayes_pls_golite062009 |
| transcription factor activity | 4.06706589695599 | bayes_pls_golite062009 |
| transcription repressor activity | 3.55154985983449 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 3.5139760613123 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 3.16896789933192 | bayes_pls_golite062009 |
| transcription activator activity | 3.10621734076555 | bayes_pls_golite062009 |
| binding | 3.02779747447702 | bayes_pls_golite062009 |
| protein binding | 1.88087411289001 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.73068440195944 | bayes_pls_golite062009 |
| chromatin binding | 1.68956710349366 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.62096064323298 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.49423102874486 | bayes_pls_golite062009 |
| transcription factor binding | 1.40653841901929 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.84983974758882 | bayes_pls_golite062009 |
| serum response element binding | 0.32349914936049 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.2679415219517 | bayes_pls_golite062009 |
| protein deacetylase activity | 0.0943601066056998 | bayes_pls_golite062009 |
| histone deacetylase activity | 0.0802156998596484 | bayes_pls_golite062009 |
