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View Structure Prediction Details

Protein: stck-PA, FBpp0297370
Organism: Drosophila melanogaster
Length: 335 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for stck-PA, FBpp0297370.

Description E-value Query
Range
Subject
Range
gi|73947291 - gi|73947291|ref|XP_541354.2| PREDICTED: similar to Zinc finger protein 606 (Zinc finger protein 328)...
486.0 [0..2] [334..2516]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLGAMHCTR CADGFEPTEK IVNSNGELWH TQCFVCAQCF RPFQDGIFYE FEGRKYCERD  60
   61 FHVLFAPCCN KCGEFVIGRV IKAMSAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.69897
Match: 2i13A
Description: No description for 2i13A was found.

Predicted Domain #2
Region A:
Residues: [88-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WHPQCFRCQL CAKELADCGF IKNQNRALCH ECNAKVKAEI TGRYVCQKCH GLIDEEPLRF  60
   61 RGEVYHGYHF SCTACGTELD STAREVKSRP GLAANDMNEL YCLRCHDKMG IPICGACRRP 120
  121 IEERVVTALG KHWHVEHFVC AKCEKPFLGH RHYEKRGLAY CETHYHQLFG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 1tf6A
Description: Transcription factor IIIA, TFIIIA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription activator activity 3.52873291636993 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
sequence-specific DNA binding 2.53101891154822 bayes_pls_golite062009
cytoskeletal protein binding 2.22104591928521 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
protein binding 2.05530362750351 bayes_pls_golite062009
transcription repressor activity 1.64349785387632 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
molecular transducer activity 1.12277938241964 bayes_pls_golite062009
signal transducer activity 1.12277938241964 bayes_pls_golite062009
structure-specific DNA binding 0.93314267845352 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
tubulin binding 0.744315484113484 bayes_pls_golite062009
microtubule binding 0.576452165256057 bayes_pls_golite062009
double-stranded DNA binding 0.53991278722671 bayes_pls_golite062009
receptor activity 0.36635758793995 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
transcription corepressor activity 0.10558148421807 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [258-335]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLCFVCNQVI GGDVFTALNK AWCVHHFACS VCDTKMTQKS KFYEYDEKPV CKKCYDRFPN  60
   61 ELRRRLRTAH EMTMKKNT

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.83
Match: 1v6gA
Description: Solution Structure of the LIM Domain of the Human Actin Binding LIM Protein 2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.84932768708444 bayes_pls_golite062009
DNA binding 3.45124926204188 bayes_pls_golite062009
nucleic acid binding 3.34875987514951 bayes_pls_golite062009
actin binding 3.16654971622305 bayes_pls_golite062009
binding 2.8684204787273 bayes_pls_golite062009
transcription activator activity 2.7888666510808 bayes_pls_golite062009
transcription factor activity 2.74592237402384 bayes_pls_golite062009
sequence-specific DNA binding 2.5486735958299 bayes_pls_golite062009
protein binding 2.35367391992524 bayes_pls_golite062009
cytoskeletal protein binding 2.30646484446275 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.23212813739998 bayes_pls_golite062009
steroid hormone receptor binding 2.02476066647216 bayes_pls_golite062009
actin filament binding 1.88094478345266 bayes_pls_golite062009
signal transducer activity 1.80369432320498 bayes_pls_golite062009
molecular transducer activity 1.80369432320498 bayes_pls_golite062009
nuclear hormone receptor binding 1.75066160573374 bayes_pls_golite062009
androgen receptor binding 1.71880332248998 bayes_pls_golite062009
receptor activity 1.7066474077575 bayes_pls_golite062009
hormone receptor binding 1.6861251260625 bayes_pls_golite062009
transcription factor binding 1.22761682002 bayes_pls_golite062009
ligand-dependent nuclear receptor activity 1.1269808729848 bayes_pls_golite062009
vinculin binding 1.11009713416006 bayes_pls_golite062009
steroid hormone receptor activity 1.06131001457937 bayes_pls_golite062009
structural constituent of ribosome 1.0478696280786 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.02819346233483 bayes_pls_golite062009
structural molecule activity 0.958501322313092 bayes_pls_golite062009
transporter activity 0.893102092384062 bayes_pls_golite062009
transmembrane transporter activity 0.7072042577999 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.551724917261005 bayes_pls_golite062009
substrate-specific transporter activity 0.489535882040485 bayes_pls_golite062009
transcription cofactor activity 0.449959641856445 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.256518766904171 bayes_pls_golite062009
transcription repressor activity 0.199267983374872 bayes_pls_golite062009
myosin binding 0.184990294745195 bayes_pls_golite062009
catalytic activity 0.133319360419662 bayes_pls_golite062009

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