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View Structure Prediction Details

Protein: ato-PA
Organism: Drosophila melanogaster
Length: 312 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ato-PA.

Description E-value Query
Range
Subject
Range
gi|476802, gi|55... - gi|551566|gb|AAA21879.1| atonal protein, pir||A40708 basic-helix-loop-helix protein ato - fruit fly ...
201.0 [0..1] [312..1]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSEIYRYY YKTSEDLQGF KTAAAEPYFN PMAAYNPGVT HYQFNGNTLA SSSNYLSANG  60
   61 FISFEQASSD GWISSSPASH RSESPEYVDL NTMYNGGCNN MAQNQQYGMI MEQSVVSTAP 120
  121 AIPVASPPAV EVMGSSNVGT CK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [143-235]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TIPASAGPKP KRSYTKKNQP STTATSTPTA AAESSASVNL YTEEFQNFDF DNSALFDDSV  60
   61 EDDEDLMLFS GGEDFDGNDG SFDLADGENQ DAA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [236-312]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGGSGKKRRG KQITPVVKRK RRLAANARER RRMQNLNQAF DRLRQYLPCL GNDRQLSKHE  60
   61 TLQMAQTYIS ALGDLLR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.221849
Match: 1nkpA
Description: Myc prot-oncogene protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.38658950816179 bayes_pls_golite062009
DNA binding 5.18654839258297 bayes_pls_golite062009
nucleic acid binding 5.05768805749761 bayes_pls_golite062009
transcription factor activity 4.78039531631248 bayes_pls_golite062009
binding 3.81829206350975 bayes_pls_golite062009
transcription factor binding 2.61163564741984 bayes_pls_golite062009
transcription activator activity 2.5495467409976 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.48787404513864 bayes_pls_golite062009
sequence-specific DNA binding 2.31910036997977 bayes_pls_golite062009
protein binding 1.59929864805879 bayes_pls_golite062009
transcription cofactor activity 1.52770895937238 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 1.46304579811572 bayes_pls_golite062009
transcription repressor activity 0.955588849035129 bayes_pls_golite062009
transcription corepressor activity 0.801830750183111 bayes_pls_golite062009
transcription coactivator activity 0.3513586903977 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle