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View Structure Prediction Details

Protein: Prosbeta2R2-PA
Organism: Drosophila melanogaster
Length: 322 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Prosbeta2R2-PA.

Description E-value Query
Range
Subject
Range
gi|12833090 - gi|12833090|dbj|BAB22385.1| unnamed protein product [Mus musculus]
248.0 [0..15] [287..3]

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Predicted Domain #1
Region A:
Residues: [1-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNGLPTLMK YPDRSPFLCG PSGFTFDNCL RNKQLKENGL EEPNSFTTGT TVVGIVFDGG  60
   61 VIIGAESRAT SGGIVFSKTC RKIIELQANI FAAGAGTARD TKALVELTRA QLELHRMNTG 120
  121 FRKVPVCCAN QMIRQLLFRF NGNIDADMII GGADNTGAHL FCTRSDGSTD TAPFTSIGSG 180
  181 YQVSMSILES RWSEDLSEES ACALACDAVA AGMKNDLCSG GKVSLCVVRC DFSVQWPEQL 240
  241 PRQVPPTRTY RLSPKPGRTT ILSTLVHPVL SWRGALALPE PGGSQEPGRG PGTSGAARGQ 300
  301 EAPRRSNSLD EPEAKRKKRG GR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.0
Match: 1iruI
Description: Proteasome beta subunit (catalytic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
endopeptidase activity 6.91642761177919 bayes_pls_golite062009
peptidase activity 6.84511694091156 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 6.5973571808298 bayes_pls_golite062009
hydrolase activity 4.47652590304822 bayes_pls_golite062009
threonine-type endopeptidase activity 2.98214579292788 bayes_pls_golite062009
threonine-type peptidase activity 2.98214579292788 bayes_pls_golite062009
catalytic activity 1.19663085909195 bayes_pls_golite062009
binding 0.982918122186083 bayes_pls_golite062009
nucleic acid binding 0.448212653390607 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle