YRC Public Data Repository - Protein Structure Prediction

Protein:	Uev1A-PA, FBpp03...
Organism:	Drosophila melanogaster
Length:	145 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Uev1A-PA, FBpp03....

Description	E-value	Query Range	Subject Range
gi\|116055009 - gi\|116055009\|emb\|CAL57086.1\| adenine-DNA glycosylase-related / MYH-related (ISS) [Ostreococcus tauri...	171.0	[0..9]	[145..82]
gi\|18417097, gi\|... - gi\|66354424\|gb\|AAY44849.1\| ubiquitinating enzyme [Arabidopsis thaliana], gi\|18417097\|ref\|NP_567791.1...	170.0	[0..12]	[145..31]
gi\|456568 - gi\|456568\|gb\|AAA64427.1\| ubiquitin conjugating enzyme	169.0	[0..12]	[145..1]
gi\|28569271 - gi\|28569271\|gb\|AAL99225.1\| ubiquitin-conjugating enzyme E2 [Gossypium raimondii] gi\|28569269 - gi\|28569269\|gb\|AAL99224.1\| ubiquitin-conjugating enzyme E2 [Gossypium thurberi]	169.0	[0..12]	[145..1]
gi\|218188784 - gi\|218188784\|gb\|EEC71211.1\| hypothetical protein OsI_03131 [Oryza sativa Indica Group] UBC5A_ORYSJ - Ubiquitin-conjugating enzyme E2 5A OS=Oryza sativa subsp. japonica GN=UBC5A PE=2 SV=1	169.0	[0..12]	[145..1]
gi\|63079015 - gi\|63079015\|gb\|AAY29571.1\| immature spike ubiquitin-conjugating enzyme 2 [Triticum aestivum]	168.0	[0..12]	[145..1]
gi\|146100778 - gi\|146100778\|ref\|XP_001468943.1\| ubiquitin-conjugating enzyme E2 [Leishmania infantum] gi\|11022580 - gi\|11022580\|emb\|CAC14238.1\| probable ubiquitin-conjugating enzyme e2-17 kda [Leishmania major] gi\|72547490, gi\|... - gi\|72547490\|ref\|XP_843237.1\| ubiquitin-conjugating enzyme E2 [Leishmania major strain Friedlin], gi\|... gi\|134073312 - gi\|134073312\|emb\|CAM72038.1\| ubiquitin-conjugating enzyme E2, putative [Leishmania infantum]	168.0	[0..12]	[145..1]
gi\|83306206 - gi\|83306206\|emb\|CAI29540.1\| ubiquitin conjugating enzyme E2 [Oryza sativa (indica cultivar-group)]	168.0	[0..12]	[145..1]

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Predicted Domain #1

Region A:
Residues: [1-145]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANTSSTGVV VPRNFRLLEE LDQGQKGVGD GTISWGLEND DDMTLTYWIG MIIGPPRTPF  60
   61 ENRMYSLKIE CGERYPDEPP TLRFITKVNI NCINQNNGVV DHRSVQMLAR WSREYNIKTM 120
  121 LQEIRRIMTM KENLKLAQPP EGSCF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.0
Match:	2a4dA
Description:	Structure of the human ubiquitin-conjugating enzyme E2 variant 1 (UEV-1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	7.07009148420636	bayes_pls_golite062009
small conjugating protein ligase activity	7.03976510657099	bayes_pls_golite062009
acid-amino acid ligase activity	6.00007452476109	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	5.06177413452771	bayes_pls_golite062009
transcription regulator activity	1.9559492182519	bayes_pls_golite062009
ligase activity	1.88059319399119	bayes_pls_golite062009
nucleic acid binding	1.83472092683523	bayes_pls_golite062009
DNA binding	1.77393825735008	bayes_pls_golite062009
binding	1.75350658654805	bayes_pls_golite062009
catalytic activity	0.891402822028799	bayes_pls_golite062009
SUMO ligase activity	0.843488104298821	bayes_pls_golite062009
protein binding	0.726328463755484	bayes_pls_golite062009
NEDD8 ligase activity	0.715654744941217	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.58835335751383	bayes_pls_golite062009
kinase activity	0.519703305315987	bayes_pls_golite062009
protein kinase activity	0.443948654247666	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.373779304908933	bayes_pls_golite062009
protein serine/threonine kinase activity	0.182854082413338	bayes_pls_golite062009
transferase activity	0.0984525836903841	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: