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View Structure Prediction Details

Protein: bl-PB
Organism: Drosophila melanogaster
Length: 413 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for bl-PB.

Description E-value Query
Range
Subject
Range
gi|113461768, gi... - gi|113461768|ref|YP_719837.1| large adhesin [Haemophilus somnus 129PT], gi|112823811|gb|ABI25900.1| ...
301.0 [0..46] [387..1455]

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Predicted Domain #1
Region A:
Residues: [1-84]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKYFEERDE DFDVRLLIHQ SLAGCVIGKG GQKIKEIRDR IGCRFLKVFS NVAPQSTDRV  60
   61 VQTVGKQSQV IEAVREVITL TRDT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 2axyA
Description: Crystal Structure of KH1 domain of human Poly(C)-binding protein-2 with C-rich strand of human telomeric DNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.76415077523249 bayes_pls_golite062009
mRNA binding 5.07455187994216 bayes_pls_golite062009
nucleic acid binding 4.78650555542715 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
2.87067043110488 bayes_pls_golite062009
transcription regulator activity 2.28364833275102 bayes_pls_golite062009
poly-pyrimidine tract binding 2.05765562493656 bayes_pls_golite062009
DNA binding 2.03207983673692 bayes_pls_golite062009
transcription factor activity 1.30278154718684 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
single-stranded RNA binding 0.981003625136521 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription repressor activity 0.392035003865213 bayes_pls_golite062009
transcription activator activity 0.324382863054631 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
transcription factor binding 0.254024117548226 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009
sequence-specific DNA binding 0.0321875054165348 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [85-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PIKGAIHNYD PMNFDRVYAD EYGGYGTGSG STRPSQRGNN RNGGGAGGVA GGAAGGNGGG  60
   61 FNAGGARGNA GGRGGADRFG GAAGGAVAGA GMGQRDNPFI NPWANGGGGD VDGFGNNAGG 120
  121 AGGFAGNSFG GGAGGPFGGG SFGNNGFGGG PSDFGGNSGN FGQAQGTNSL PSLGSFSQNQ 180
  181 GGTSSLPSLG SFGQNPGGPG GLGNGLSGGA NGGVGTLGGA NGAGGFNAVG GANGGPNG

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.06
Match: 1wckA
Description: Crystal structure of the C-terminal domain of BclA, the major antigen of the exosporium of the Bacillus anthracis spore.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [323-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPNAATNVPQ GHDPNNSTQV TIPKELAGAI IGKGGGRIRR IRNESSAYIT IDEPLPNSND  60
   61 RIITISGTPK QIQMAQYLLQ QSVHENGRRN I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1zziA
Description: Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.76415077523249 bayes_pls_golite062009
mRNA binding 5.07455187994216 bayes_pls_golite062009
nucleic acid binding 4.78650555542715 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
2.87067043110488 bayes_pls_golite062009
transcription regulator activity 2.28364833275102 bayes_pls_golite062009
poly-pyrimidine tract binding 2.05765562493656 bayes_pls_golite062009
DNA binding 2.03207983673692 bayes_pls_golite062009
transcription factor activity 1.30278154718684 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
single-stranded RNA binding 0.981003625136521 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription repressor activity 0.392035003865213 bayes_pls_golite062009
transcription activator activity 0.324382863054631 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
transcription factor binding 0.254024117548226 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009
sequence-specific DNA binding 0.0321875054165348 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle