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View Structure Prediction Details

Protein: FBpp0303033, Pcl-PA
Organism: Drosophila melanogaster
Length: 1043 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0303033, Pcl-PA.

Description E-value Query
Range
Subject
Range
gi|54635928, gi|... - gi|54635928|gb|EAL25331.1| GA18665-PA [Drosophila pseudoobscura], gi|125808452|ref|XP_001360756.1| G...
659.0 [0..2] [1040..1]

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Predicted Domain #1
Region A:
Residues: [1-107]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMNNHFHLQH DHPPQNVAHP FMQQPSTAVP SAPPATYGYL AQPAGQQPQW MTTTYQILPP  60
   61 SVGPATVAKR YYATTGPQTT HPTHPSTIQI TNSFAQQSTP PKQQAAT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [108-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SCSPFKANNI RIISTAPSVY SLNKPPQEAH STYAPVQSYY LPSGGGQTAG QINLLAASGT  60
   61 GKQLQPPPLV P

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [179-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTNSTSPPST VVLDRINICI NNHYTETPTS LSSSLTTAQQ PSPIIPAIQH KAILPLIDSS  60
   61 TADSSSCSSS SVSSSSYSGT ATTSAAVVIV DEPDSTTTTP QTPPTTPEAM SSPGKSSPSP 120
  121 PLLATQSLLK GVNSMKPSFK TVEAAPPTPP T

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [330-483]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPSPPPPPPA PPVAAPSPAV TYALQEDVFI KCNDGRFYLG TIIDQTSDQY LIRFDDQSEQ  60
   61 WCEPDKLRKL GGGSSITAGG GGASTTESTN TSPSGPMCVA CKRSDIEDVV EICERCGRGY 120
  121 HRGCTVEIVT GSGIWSCKRC AKPMKMQQPV SHKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.0
Match: 2ysmA
Description: No description for 2ysmA was found.

Predicted Domain #5
Region A:
Residues: [484-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKPAGICRQL PYHADKLSWD EKHRVNEEQI YCYCGKPGKF DHNMLQCCKC RNWFHTQCMQ  60
   61 NFKKKLLRGD MFFVFCCTVC NNGIEFVRRM QIEWVDVL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.48
Match: 1wepA
Description: Solution structure of PHD domain in PHF8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.84543733401722 bayes_pls_golite062009
binding 2.84147289283175 bayes_pls_golite062009
histone binding 2.70040054044692 bayes_pls_golite062009
DNA binding 2.61461572393763 bayes_pls_golite062009
nucleic acid binding 2.59290953932215 bayes_pls_golite062009
transcription repressor activity 2.05685078783854 bayes_pls_golite062009
transcription factor activity 1.59046392323038 bayes_pls_golite062009
methylated histone residue binding 1.34633512809029 bayes_pls_golite062009
protein binding 1.32925779020231 bayes_pls_golite062009
histone acetyltransferase activity 0.840604267149776 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.840604267149776 bayes_pls_golite062009
transcription activator activity 0.663225694514289 bayes_pls_golite062009
chromatin binding 0.238939737856273 bayes_pls_golite062009
sequence-specific DNA binding 0.0471610688739243 bayes_pls_golite062009
transcription factor binding 0.0293954104210474 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [582-670]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HIALYNLRKH QHQKYHHLLN DIWPFILEQR HQLPICEKWR TLPETALMER LKQTLKDYSD  60
   61 RFVCGREFKR APAFYALRHS GPPHIPKVF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [671-853]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEPHEELSDE LLEKRFKLML MPEEPDEGAN ELPKRVPKDV YEFNTDEDDP VETSEDEIPI  60
   61 KQIIEKAKKQ AAQKADKHDE LPLKPDLADD NANDGDPGKL PAPIPPLLDA NSSRKRKAFR 120
  121 LSKRYDNSRN HCDLSSDENS SSSRGTSSLD LIIPPPVNFL GRNNPFLMAT PKKASQGRSI 180
  181 SVG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [854-1043]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGVGVNGIIN SIFKLKGTSK EQPRMVRTIK RRLSAKDITI GPNQEVRRRR TRRLTTAIEV  60
   61 ISTTTINPIP SHYLPIYAKD LQPPAPPMGK PTHGRLLRQR PQKQSPSQSR RNSTSSTATS 120
  121 SSSNGIGAPG HSMLDLKQSV NKYFGGAMNR IDAGEPFAIR AKRRMGNGQV QYLVEWGGDT 180
  181 ATTAIGLLGN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle