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View Structure Prediction Details

Protein: l(2)k01209-PC, l...
Organism: Drosophila melanogaster
Length: 626 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for l(2)k01209-PC, l....

Description E-value Query
Range
Subject
Range
l(2)k01209-PA - The gene lethal (2) k01209 is referred to in FlyBase by the symbol Dmel\l(2)k01209 (CG4798, FBgn0022...
452.0 [0..95] [626..30]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSITFLCSK SGHNTNNNSI NSSNNDVPKG AKANSAFAAA SAGLLTIANH QQQQLLQQPH  60
   61 QQQQQQQQQH HQQSKVKAIA AKTNGHIDDR SLSDVTEQLY VDPYADLSNG LPGDLNCCPA 120
  121 SPTTVPAKAS LDSPLKRSGR RQRTTSIGNQ TTTANPSECI IRANNRTIYT AGRPPWYNCA 180
  181 GQQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VEPFVIGICG GSASGKTTVA EKIIESLDVP WVTLLSMDCF YKILNEKQHE QALINEYNFD  60
   61 HPDAFDIELL LDVLTKLKEG RKVEVPVYNF VTHGRESQTK TMYGANVIIF EGILTFHSPE 120
  121 VLKLLDMKIF VDTDPDIRLA RRLRRDISQR GRDLKGVLKQ YLNMVKPSYC NYIAPTMAHA 180
  181 DIIVPRGGDN KVAIHLIVQH VHTQLQLRGF KLRETLANSY KDQP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.522879
Match: 2jeoA
Description: No description for 2jeoA was found.

Predicted Domain #3
Region A:
Residues: [408-626]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHSLHLLHP TPQIKGLHTF IRCRNTSRDE FIFYSKRLIR LVIEYALSLF PFKKTTVETP  60
   61 QGVLYEGKRM ESRKICGVSI LRAGETMEQA VCDVCKDIRI GKILIQTNLK TGEPELYYLR 120
  121 LPKDIKDYKV ILMDATVATG AAAMMAIRVL LDHDVPEDNI ILASLLMAEI GVHSIAYAFP 180
  181 KVKIVTSALD PEINSKFYVI PGIGNFGDRY FGTEPSDEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 49.69897
Match: 1bd3D
Description: Uracil PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
uracil phosphoribosyltransferase activity 3.97944228585882 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 3.91023158228049 bayes_pls_golite062009
adenine phosphoribosyltransferase activity 3.07502596276449 bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity 2.97347277288245 bayes_pls_golite062009
transferase activity 2.73727660668741 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 2.53679639481311 bayes_pls_golite062009
catalytic activity 2.30431811394775 bayes_pls_golite062009
nucleobase binding 1.70525606708275 bayes_pls_golite062009
purine binding 1.24786927434743 bayes_pls_golite062009
ribose phosphate diphosphokinase activity 0.947697983706416 bayes_pls_golite062009
binding 0.847513071499147 bayes_pls_golite062009
diphosphotransferase activity 0.749909396904601 bayes_pls_golite062009
nucleic acid binding 0.552133387792911 bayes_pls_golite062009
DNA binding 0.439741935655503 bayes_pls_golite062009
transcription regulator activity 0.396538943915776 bayes_pls_golite062009
amidophosphoribosyltransferase activity 0.360901350940423 bayes_pls_golite062009
orotate phosphoribosyltransferase activity 0.148898393751978 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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