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View Structure Prediction Details

Protein: Psi-PB
Organism: Drosophila melanogaster
Length: 796 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Psi-PB.

Description E-value Query
Range
Subject
Range
Psi-PC - The gene P-element somatic inhibitor is referred to in FlyBase by the symbol Dmel\Psi (CG8912, FBgn0...
293.0 [0..1] [796..1]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDFQQQGIN QSQALAQAIQ RAKQIAAKIQ PSQQGGGTAG PSPPSSGGGP GFKRINDDGD  60
   61 SGPESKRSLG SPEYANNSSN MSSGSGGGGG GGGGPGGASI TQAIAQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [107-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAVAARLAA SAGTSCEEQI RLPESVAGAF MGRSSNDTIT HIQAESGVKV QVMQDQDRVI  60
   61 MLRGQRDTVT KGREMIQNMA NRAGGGQVEV LLTINMPPPG PSGYPPYQEI MIPGAKVGLV 120
  121 IGKGGDTIKQ LQEKTGAKMI IIQDGPNQEL IKPLRISGEA QKIEHAKQMV LDLIAQKDAQ 180
  181 GQQQG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.69897
Match: 2annA
Description: No description for 2annA was found.

Predicted Domain #3
Region A:
Residues: [292-512]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRGGGGGGGG PGMGFNNFNN GNGGESTEVF VPKIAVGVVI GKGGDMIRKI QTECGCKLQF  60
   61 IQGKNDEMGD RRCVIQGTRQ QVDDAKRTID GLIENVMQRN GMNRNGNGGG GGPGGDSGNS 120
  121 NYGYGYGVNH AQGGREEITF LVPASKCGIV IGRGGETIKL INQQSGAHTE MDRNASNPPN 180
  181 EKLFKSKGTT DQVEAARQMI SEKINMELNV ISRKPIGGGP G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.154902
Match: 1j4wA
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.76415077523249 bayes_pls_golite062009
mRNA binding 5.07455187994216 bayes_pls_golite062009
4.82131641133915 bayes_pls_golite062009
nucleic acid binding 4.78650555542715 bayes_pls_golite062009
binding 3.45962790790935 bayes_pls_golite062009
transcription regulator activity 2.28364833275102 bayes_pls_golite062009
poly-pyrimidine tract binding 2.05765562493656 bayes_pls_golite062009
DNA binding 2.03207983673692 bayes_pls_golite062009
transcription repressor activity 1.87340518658135 bayes_pls_golite062009
transcription factor activity 1.30278154718684 bayes_pls_golite062009
protein binding 1.16541072642796 bayes_pls_golite062009
single-stranded RNA binding 0.981003625136521 bayes_pls_golite062009
mRNA 3'-UTR binding 0.489176583045793 bayes_pls_golite062009
transcription activator activity 0.324382863054631 bayes_pls_golite062009
structure-specific DNA binding 0.32222928997178 bayes_pls_golite062009
transcription factor binding 0.254024117548226 bayes_pls_golite062009
catalytic activity 0.113112541746059 bayes_pls_golite062009
single-stranded DNA binding 0.1069917291606 bayes_pls_golite062009
sequence-specific DNA binding 0.0321875054165348 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [513-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGGGNSGGGQ NNSHHNQQQG GYGGQNQMQG GDPNSGAGYQ QQPWGGPYGQ QGWDPSGQQQ  60
   61 QMAMANQGGS AAGGASGGQD YSAQWIEYYK QMGCHREAEM IEQQMKAKQA GGSSGPVQQQ 120
  121 QPQQQQQSQQ QTGGAGAGGA DYSAQWAEYY RSVGKIEEAE AIEKTLKNKQ NGSGGQSST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [692-796]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPSQGGSGQ QQPNPAAAAA AAAAAAAAAG GYGQSMTPTQ YAQYSQYYAA AAAAGGQPQG  60
   61 APQPGGGQSG GPPGNYPGNY PGAGYGGYPG APGQQQQKSH KNDNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle