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View Structure Prediction Details

Protein: FBpp0307628
Organism: Drosophila melanogaster
Length: 929 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0307628.

Description E-value Query
Range		 Subject
Range
Strn-Mlck-PK - The gene Stretchin-Mlck is referred to in FlyBase by the symbol Dmel\Strn-Mlck (CG18255, FBgn0013988...
 536.0 [0..4] [929..8345]

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Predicted Domain #1
Region A:
Residues: [1-167] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQLESYPEN GIRLLRMRDV TASRSGEICL QVKHPQAEFR RIPTTRTYTS LLVLPAIRGN  60
   61 SSSSSLAARS CILTRPEDCT ALIGGHVRLS VRYEPFPGTK VIWYKACHPI VESSNVTIRT 120
  121 TSQQSTLYIT DISADDSGKY TVEVMNDYGV EAAAASVAVE GPPEPPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 1djsA
Description: Fibroblast growth factor receptor, FGFR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
telethonin binding 3.28978580589536 bayes_pls_golite062009
binding 3.17641566810715 bayes_pls_golite062009
cytoskeletal protein binding 2.59139016029428 bayes_pls_golite062009
alpha-actinin binding 2.4388976537381 bayes_pls_golite062009
protein binding 2.22855404705168 bayes_pls_golite062009
nucleic acid binding 2.13338563453164 bayes_pls_golite062009
transcription regulator activity 2.09812904791121 bayes_pls_golite062009
tubulin binding 2.08792429244614 bayes_pls_golite062009
calmodulin-dependent protein kinase activity 2.00225422923859 bayes_pls_golite062009
DNA binding 1.94748821300258 bayes_pls_golite062009
actin binding 1.75411721656376 bayes_pls_golite062009
antigen binding 1.63189745559168 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.47807703678891 bayes_pls_golite062009
actinin binding 1.40575499798071 bayes_pls_golite062009
kinase activity 1.39954632432505 bayes_pls_golite062009
protein kinase activity 1.36635494500222 bayes_pls_golite062009
gamma-tubulin binding 1.27899491476578 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.20218845204373 bayes_pls_golite062009
transcription factor activity 1.19760118797575 bayes_pls_golite062009
transcription activator activity 1.18640380933408 bayes_pls_golite062009
actin filament binding 1.05147425412339 bayes_pls_golite062009
receptor activity 0.991682709371995 bayes_pls_golite062009
structural constituent of cytoskeleton 0.965431415167831 bayes_pls_golite062009
transferase activity 0.756515665570446 bayes_pls_golite062009
transmembrane receptor activity 0.627651343374052 bayes_pls_golite062009
structural molecule activity 0.567620977360967 bayes_pls_golite062009
protein serine/threonine kinase activity 0.564762108830441 bayes_pls_golite062009
signal transducer activity 0.521883122362181 bayes_pls_golite062009
molecular transducer activity 0.521883122362181 bayes_pls_golite062009
peptide antigen binding 0.32810917910919 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [168-660] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQPSVSLGPD RVAVAWCGPP YDGGCMITGF IIEMQTIGDE NCDEDSWQQV TRVVDSLAYT  60
   61 VKNLQPERQY RFRVRAENIH GRSAPGQASE LVQITNTPQR STSSDASDRF GQATVSVQSG 120
  121 GDFKSRFEII EELGKGRFGI VYKVQERGQP EQLLAAKVIK CIKSQDRQKV LEEISIMRAL 180
  181 QHPKLLQLAA SFESPREIVM VMEYITGGEL FERVVADDFT LTEMDCILFL RQVCDGVAYM 240
  241 HGQSVVHLDL KPENIMCHTR TSHQIKIIDF GLAQRLDTKA PVRVLFGTPE FIPPEIISYE 300
  301 PIGFQSDMWS VGVICYVLLS GLSPFMGDTD VETFSNITRA DYDYDDEAFD CVSQEAKDFI 360
  361 SQLLVHRKED RLTAQQCLAS KWLSQRPDDS LSNNKICTDK LKKFIIRRKW QKTGNAIRAL 420
  421 GRMANLSVSR RNSAIAMGVL SSPRPSISGL GMLTTSAIGS GTSSQMTSLH EEEDDFSGEM 480
  481 PPVEKRTVLK LRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.39794
Match: 2acxA
Description: No description for 2acxA was found.

Predicted Domain #3
Region A:
Residues: [661-764] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSQCSERSDS GYSECSNCSG AQETLLLSLA KSKLEAIAKA STLPTVVHDT EQPVSLELPT  60
   61 KGEAIMRSDF TNTIKMRKKS LEDSAAREKP RSKPQVKPLL CESK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 1koaA
Description: TWITCHIN KINASE FRAGMENT (C.ELEGANS), AUTOREGULATED PROTEIN KINASE AND IMMUNOGLOBULIN DOMAINS
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [765-929] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKVSQLKDRF QVSPAPASAS ASASAANKPP LAYGPFKIAK VASVGRISRT EEPGRSGRGA  60
   61 PSVSGKGKSP QVRSMPSSPL PQRSATPTRL MSQRVREAAE RLAQQHTVAS AQRHLGNGRG 120
  121 TGTGNGNGNS NSNGNGNGNT AETNRESRAR RLINRFNSET QHITS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle