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View Structure Prediction Details

Protein: Poxn-PA, FBpp0302942
Organism: Drosophila melanogaster
Length: 425 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Poxn-PA, FBpp0302942.

Description E-value Query
Range
Subject
Range
gi|2137624, gi|7... - gi|736381|gb|AAA64491.1| Pax7 [Mus musculus], pir||I49265 paired box transcription factor pax7 - mou...
257.0 [0..7] [299..1]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHTGQAGVN QLGGVFVNGR PLPDCVRRRI VDLALCGVRP CDISRQLLVS HGCVSKILTR  60
   61 FYETGSIRPG SIGGSKTKQV ATPTVVKKII RLKEENSGMF AWEIREQLQQ QRVCDPSSVP 120
  121 SISSINRILR NSGLWTDEM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.522879
Match: 1k78A
Description: Pax-5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
sequence-specific DNA binding 3.5139760613123 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
transcription activator activity 3.10621734076555 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
protein binding 1.88087411289001 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [140-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSQQNAAAA AAAAAAAAHQ AGSGPSNGYG GQAPPPPVTV APPTPAATPS IARYAKPPAL  60
   61 MMNSAGEMPI KPAPKMPPSM GHGHSHGLNP NVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [233-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLDLSYSALH KHWLWNPSLL YYTQAHIQAQ AAASGGQFLP YAGGYLPHAM AAAAASSTSA  60
   61 LGGFTKSESS IDLSTPGAAG DALSDCDSGK SSPAALSLTA SGGGNGAGSA PEASPGSTLS 120
  121 HSRKRNPYSI EELLKKPEKR LRLDSNRLEC LESSSCESSQ DSPVAPPLET PEDEDPAEAE 180
  181 EEQEEEDSVE VVN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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