YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: Sin3A-PD
Organism: Drosophila melanogaster
Length: 1751 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sin3A-PD.

Description E-value Query
Range
Subject
Range
Sin3A-PB, FBpp02... - The gene Sin3A is referred to in FlyBase by the symbol Dmel\Sin3A (CG8815, FBgn0022764). It is a pro...
1319.0 [0..1] [1750..1]

Back

Predicted Domain #1
Region A:
Residues: [1-914]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRTRVDEV QFGTRPVPQT SGGVGVGVVG VTGGGPTSGG GGTATVGVNT TGVTIGTVVP  60
   61 SAHNATISGI GSIHHRILTP QHGGAQTIAY LPSTTPTATN LKTTTSIVDS TTAGGPVGAG 120
  121 AQVAVGVGSA AGGGGVVVST GSTGTQTLQY TTSYSVASIQ AGGTLKANTA DGANTVQIHV 180
  181 TGGGAANNPA SAQTVSSSSQ TGTIRQRTIS GTQTVATAVG NLATISQQQP VQQSPLGKAQ 240
  241 TPPSSVVANS IPVGGTTPPQ GQSGNATPRL KVEDALSYLD QVKYQYADQP QIYNNFLDIM 300
  301 KEFKSHCIDT PGVIERVSTL FKGHTELIYG FNMFLPPGYK IEIHSDALGC SVPVVSMPSP 360
  361 PGAPTSTGTV HMLTGNSSMS GAGHIAIKTT NAATLTPAAG AGAAAAAAAV AQIQSAGAVN 420
  421 LMTHGGASLT QTTIHALQQA TPPQSQSPGG GHVHVSVTNS TAANAVVPGQ PGISVSAHNV 480
  481 PQNYSRDRER ATITPTGQVA GAAANVNASA SIVVGGPPTP NSLSELSPHG GAGGGPGAGA 540
  541 AQHNLHHIQQ AHQSILLGET GQQNQPVEFN HAITYVNKIK NRFQNQPAKY KKFLEILHDY 600
  601 QREQKVMKEG SLNQGKMLTE QEVYTQVAKL FGQDEDLLRE FGQFLPDATN HQSGQYMSKS 660
  661 ASVHNDHGKR PTATLSGGAH ITMSSASPAP SGSPLHLGAT TLPQIDKSAH AAAIGNLSAV 720
  721 NTSVSIKTYN NNQQQQNHVI GSGLNATRND ILFEKDYHAG LQQQAHQRGA GVGGHHHLAG 780
  781 TAAGANIGRP GVGASVMVSY DKEHRNNHHV QKYVGHAPNQ NLTHGHNAKK SPSYGIPSVI 840
  841 GSMPHISDNS LDRSSPGISY ATPPLPSGPH GQHNSGSATR RPGDDSLVGH YASGAPPAKR 900
  901 PKPYCRDVSF SEAS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.522879
Match: 1y0fB
Description: No description for 1y0fB was found.

Predicted Domain #2
Region A:
Residues: [915-1008]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKCTISDAAF FDKVRKALRS PEVYDNFLRC LTLFNQEIVS KTELLGLVSP FLMKFPDLLR  60
   61 WFTDFLGPPS GQPAGGLIDG MPLAATQRQG GGSS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.86
Match: 2f05A
Description: No description for 2f05A was found.

Predicted functions:

Term Confidence Notes
protein deacetylase activity 4.85550095681437 bayes_pls_golite062009
histone deacetylase activity 4.80822599235131 bayes_pls_golite062009
transcription repressor activity 4.25514230798992 bayes_pls_golite062009
transcription regulator activity 3.82193713323077 bayes_pls_golite062009
deacetylase activity 3.68673303770777 bayes_pls_golite062009
transcription corepressor activity 3.30769773581294 bayes_pls_golite062009
nucleic acid binding 2.83214064778422 bayes_pls_golite062009
DNA binding 2.82083682611814 bayes_pls_golite062009
transcription factor binding 2.73494763175272 bayes_pls_golite062009
transcription cofactor activity 2.59356984380124 bayes_pls_golite062009
binding 2.59005615358803 bayes_pls_golite062009
transcription factor activity 1.99794029160509 bayes_pls_golite062009
protein binding 1.36724461365736 bayes_pls_golite062009
transcription coactivator activity 0.918453145717461 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.864804910849344 bayes_pls_golite062009
transcription activator activity 0.570282420961288 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.536470369536903 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.512364998565023 bayes_pls_golite062009
catalytic activity 0.30211814650972 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [1009-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSHDRGTSH QSAAEYVQDV DLSSCKRLGA SYCALPQSTV PKKCSGRTAL CREVLNDKWV  60
   61 SFPTWASEDS TFVTSRKTQF EETIYRTEDE RFELDLVIEV NSATIRVLEN LQKKMSRMST 120
  121 EELSKFHLDD HLGG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 64.376751
Match: PF08295.3
Description: No description for PF08295.3 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [1143-1262]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSQTIHQRAI HRIYGDKSGE IITGMKKNPF VAVPIVLKRL KVKEEEWREA QKTFNKQWRE  60
   61 QNEKYYLKSL DHQAINFKPN DMKALRSKSL FNEIETLYDE RHDQEDDAME PFGPHLVLPY 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1263-1551]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDKTILDDAA NLLIHHVKRQ TGIQKQEKQK IKQIIRQFVP DLFFAPRQPL SDDERDDAFP  60
   61 FLVDDNTKMD VDSPLGRTES STRNAKSTPS ESASPARSNA STSSVTPAGI KKETDDSKAT 120
  121 TGSFAPASSA TASSATPVDD ATPSTSSAAA AASAASSSTV SGTEGKPKDD PLSSHKEEGA 180
  181 GSTSSGVATS PRQAQDTAGA GVDVEIKLEH PADFSNPKLL PPHAHGQRED ESYTLFFANN 240
  241 NWYLFLRLHA ILCDRLHVMY ERARLLAIEE ERCRVNRRES TATALRLKP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.41
Match: 1h1kI
Description: THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1552-1673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPEIQVEDYY PTFLDMLKNV LDGNMDSNTF EDTMREMFGI YAYISFTLDK VVSNAVRQLQ  60
   61 YCVTERAALD CVELFATEQR RGCTGGFCRD AHKTFDREMS YQRKAESILN EENCFKVYIY 120
  121 KI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1674-1751]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DCRVTIELLD SEPEEVDKPA ALKAQKFSKY VERLANPALG GGGNTGRSDS ALGNDSVVDG  60
   61 SDIKTEADED TAEVNTKA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle