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View Structure Prediction Details

Protein: pds5-PA, FBpp0297204
Organism: Drosophila melanogaster
Length: 1218 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pds5-PA, FBpp0297204.

Description E-value Query
Range
Subject
Range
gi|114593776 - gi|114593776|ref|XP_526554.2| PREDICTED: SCC-112 protein [Pan troglodytes]
867.0 [0..3] [1217..104]

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Predicted Domain #1
Region A:
Residues: [1-1033]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADIVYPTGC RPLVEDLGTD ELIRRLKTLA NVLQTMDQDD NLYQQYIPLA LHLLDDFFMQ  60
   61 HPSRDVQLLI ACCVADVLRV YAPEAPYKEQ DQIKTIFKFF IKQLHGLKDP RDPSFKRYFY 120
  121 LLENLAFVKS FNMCFELEDC QEIFQDLFST IFKIVNDQHS VKVTNFFLDV LSPLITEADN 180
  181 LSVELLDLIL INIVEPYKSN NKFACQLTEQ LLTKTGDALE STIKMFFNRA LVMDKPNTKL 240
  241 SITNKIYDII YELNRINAGL LCSVLPQLEN KLLSTDDAER LKATTLLSRM FSEKDSQLAK 300
  301 KYPNLLKIFF GRFCDITEPV RIKCVQSSMH FLLNHPSLQH DITEKLRLRN HDLDEVVRHE 360
  361 VVMAIVETAK RDFTLVLEAP DLLEIVRERT LDKKYKIRRD AMNGLAYIYK RAICEPNDLS 420
  421 TGLKVRVDWI KNKILHGYYK VGLEDRLLVE RLLITCLVPY KLAPEERMKK LYHLLGDLDA 480
  481 NATKAFVELQ KNQMKTRNTV SDWIKLHHSK EFTPRVLSQL SAKQANIAKL LPDPLKAAEY 540
  541 LTQFSNNLRK DAQLLRCINI VLKRDVSCRE CADTMGVLLK KLGAHVQSNL YYNTVKMLIE 600
  601 RVASVMVDKE SIGVLISLIE QCIEKGSMCE EIGISAQEAG ERGLKLLAML SYVFSAHFFT 660
  661 DTSLRHLISL LSYEQDYVAP LVLKTLTHLG RYQPLIDDPT PAILDELAPV CKDFALIGTP 720
  721 KQAKHAVRCI FVNSQSSAST DGATSGAGSA STTTQTVHPI FNEIIETLRL KLTPNCEHQR 780
  781 TKIVTLGHIA YNMPQAFLTP IKNMIARRIV KELLIQEVPA QRDYELPEDS DWCAQEKLPP 840
  841 DTLCKLDALK AMARWLLGLR TDEHAAQKTF RMLAAFVNQR GDLLGQNRLC GAEKSWLRLG 900
  901 AACAMLKVCE QKGVGDQYSA EQYLQLSQLM ADPVPEVREI FARKLHKGLS RSLPRNCLPL 960
  961 DFMGLYVLAG LETERKLQDL VRHYAETDVN KRREYLKTVA MTSPDSSTES QSLHILPDYM1020
 1021 LAFAIPVLVH DPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.39794
Match: 1u6gC
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein transporter activity 3.05338750264476 bayes_pls_golite062009
binding 2.86831493830281 bayes_pls_golite062009
protein binding 1.63705839411934 bayes_pls_golite062009
cytoskeletal protein binding 1.61037669901273 bayes_pls_golite062009
transporter activity 1.55621630624352 bayes_pls_golite062009
substrate-specific transporter activity 1.33334123659384 bayes_pls_golite062009
protein transmembrane transporter activity 1.15447282085461 bayes_pls_golite062009
actin binding 0.891762677781115 bayes_pls_golite062009
nucleic acid binding 0.804909841250605 bayes_pls_golite062009
signal sequence binding 0.55352931702601 bayes_pls_golite062009
transmembrane transporter activity 0.350388174853674 bayes_pls_golite062009
structure-specific DNA binding 0.331309559699391 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.141331164449492 bayes_pls_golite062009
transcription regulator activity 0.123389318446902 bayes_pls_golite062009
DNA binding 0.089209424262799 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [1034-1141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTNHEDYVQL RKMEKCLRFI LEPLMAKRET FVHSFYKQLL QLIKHREFSL GSDKRDNYKM  60
   61 WALCDLAMYI IDSKFSPFDG NTSTFSMPLA LPEMYYKEPA VANFQNND

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [1142-1218]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VYIPLDVYTL GAKSTSKAAA TAMTTSRAAV APKRPAEQSI MDDENPQENN LFDNIRAADT  60
   61 TEPMAKRTRA GAASAKS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle