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Protein Overview: pds5-PA, FBpp0297204

General Information:
Name(s) found: FBpp0297204 [FlyBase]
pds5-PA / FBpp0087082 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • type=protein; loc=2R:join(7916080..7916160,7916222..7916607,7916671..7916878,7916937..7917105,7917169..7917910,7917975..7918238,7918296..7918389,7918452..7919297,7919363..7919499,7919561..7919640,7919702..7919967,7920040..7920330,7920394..7920486); ID=FBpp0297204; name=pds5-PB; parent=FBgn0260012,FBtr0306062; dbxref=REFSEQ:NP_001246271,GB_protein:AFH08025,FlyBase:FBpp0297204,FlyBase_Annotation_IDs:CG17509-PB; MD5=5b5a9549835036a6e69010cd346699ad; length=1218; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\pds5 (CG17509, FBgn0260012). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7915497..7921201. It has the cytological map location 48D7-48D6. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: sister chromatid cohesion; karyosome formation. 13 alleles are reported. The phenotypes of these alleles are annotated with: mitotic cohesin complex; salivary gland; polytene chromosome; condensed chromosome; imaginal disc; larval brain. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1218 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cohesin complex [IDA]
    Biological Process: sister chromatid cohesion [IMP]
    karyosome formation [IMP]
    chromosome segregation [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADIVYPTGC RPLVEDLGTD ELIRRLKTLA NVLQTMDQDD NLYQQYIPLA LHLLDDFFMQ  60
   61 HPSRDVQLLI ACCVADVLRV YAPEAPYKEQ DQIKTIFKFF IKQLHGLKDP RDPSFKRYFY 120
  121 LLENLAFVKS FNMCFELEDC QEIFQDLFST IFKIVNDQHS VKVTNFFLDV LSPLITEADN 180
  181 LSVELLDLIL INIVEPYKSN NKFACQLTEQ LLTKTGDALE STIKMFFNRA LVMDKPNTKL 240
  241 SITNKIYDII YELNRINAGL LCSVLPQLEN KLLSTDDAER LKATTLLSRM FSEKDSQLAK 300
  301 KYPNLLKIFF GRFCDITEPV RIKCVQSSMH FLLNHPSLQH DITEKLRLRN HDLDEVVRHE 360
  361 VVMAIVETAK RDFTLVLEAP DLLEIVRERT LDKKYKIRRD AMNGLAYIYK RAICEPNDLS 420
  421 TGLKVRVDWI KNKILHGYYK VGLEDRLLVE RLLITCLVPY KLAPEERMKK LYHLLGDLDA 480
  481 NATKAFVELQ KNQMKTRNTV SDWIKLHHSK EFTPRVLSQL SAKQANIAKL LPDPLKAAEY 540
  541 LTQFSNNLRK DAQLLRCINI VLKRDVSCRE CADTMGVLLK KLGAHVQSNL YYNTVKMLIE 600
  601 RVASVMVDKE SIGVLISLIE QCIEKGSMCE EIGISAQEAG ERGLKLLAML SYVFSAHFFT 660
  661 DTSLRHLISL LSYEQDYVAP LVLKTLTHLG RYQPLIDDPT PAILDELAPV CKDFALIGTP 720
  721 KQAKHAVRCI FVNSQSSAST DGATSGAGSA STTTQTVHPI FNEIIETLRL KLTPNCEHQR 780
  781 TKIVTLGHIA YNMPQAFLTP IKNMIARRIV KELLIQEVPA QRDYELPEDS DWCAQEKLPP 840
  841 DTLCKLDALK AMARWLLGLR TDEHAAQKTF RMLAAFVNQR GDLLGQNRLC GAEKSWLRLG 900
  901 AACAMLKVCE QKGVGDQYSA EQYLQLSQLM ADPVPEVREI FARKLHKGLS RSLPRNCLPL 960
  961 DFMGLYVLAG LETERKLQDL VRHYAETDVN KRREYLKTVA MTSPDSSTES QSLHILPDYM1020
 1021 LAFAIPVLVH DPRFTNHEDY VQLRKMEKCL RFILEPLMAK RETFVHSFYK QLLQLIKHRE1080
 1081 FSLGSDKRDN YKMWALCDLA MYIIDSKFSP FDGNTSTFSM PLALPEMYYK EPAVANFQNN1140
 1141 DVYIPLDVYT LGAKSTSKAA ATAMTTSRAA VAPKRPAEQS IMDDENPQEN NLFDNIRAAD1200
 1201 TTEPMAKRTR AGAASAKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1033] PSI-BLAST 38.39794 Crystal Structure of The Cand1-Cul1-Roc1 Complex
    2 View Details [1034..1141] MSA 1.124972 View MSA. No confident structure predictions are available.
    3 View Details [1142..1218] MSA 3.049991 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein transporter activity
    		•  3.05338750264476 bayes_pls_golite062009
  • binding
    		•  2.86831493830281 bayes_pls_golite062009
  • protein binding
    		•  1.63705839411934 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.61037669901273 bayes_pls_golite062009
  • transporter activity
    		•  1.55621630624352 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.33334123659384 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  1.15447282085461 bayes_pls_golite062009
  • actin binding
    		•  0.891762677781115 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.804909841250605 bayes_pls_golite062009
  • signal sequence binding
    		•  0.55352931702601 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.350388174853674 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.331309559699391 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.141331164449492 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.123389318446902 bayes_pls_golite062009
  • DNA binding
    		•  0.089209424262799 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle