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View Structure Prediction Details

Protein: StIP-PA
Organism: Drosophila melanogaster
Length: 794 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for StIP-PA.

Description E-value Query
Range		 Subject
Range
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
 715.0 [0..2] [793..768]

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Predicted Domain #1
Region A:
Residues: [1-124] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVENLHTSV ACNRCTECAD WGPNGWIAYG ACNAIAIMDP KFQGNSAKVL FTLVEHTKRV  60
   61 NTVRWLDCDK LLSGGDDAIA ILWELDETGT TKSFTLKGHT SGVNTVDGIR QQDGSWLLAT 120
  121 AAAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.30103
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [125-686] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTIKLWTFQD NNYVCFQTIS LSDGFCFCLR LQLLPKSNQV LLAFSGDDET VSLWSEQVET  60
   61 AGEGDSLGRQ FQRKHKLTGH EDWVRGLDFV VDGEDLLLAS GSQDNFIRLW RIAPRSKEQM 120
  121 QENRVDLHQL SHNDDEIKVE EKILQLGKEA WYAVSLESVL YGHEGWIYGV HWHKTPDQEL 180
  181 RLLSASIDKT VIIWAPTEEG IWLEEVRVGE VGGNSVGFYG GKFSGDGHSI MAHSYQGGFH 240
  241 IWSQDPDRPQ LWTPGVIVGG HYGEVRDLAW EHSGAYLMTA SADQTTRLHA PWLQDGANPT 300
  301 WHELARPQIH GYDMQALALL SRYKFASGAE EKIVRTFQAP ANFIENFRHI SGIENDDAGD 360
  361 VLLDSLPKGA SVPSLGLSNK AVYKVDSEVE STSKTSKDEY PDNYFVPIAL ETPPQEETLM 420
  421 QNTLWPELQK LYGHGYEIFA LAATADGSLL ASTCKASNAE HAQIILWNPS NWKQIQKLSG 480
  481 HQLTVTQLSF SPDSRYLLSV SRDRRWCLYE RQDSSVSYQL VASTDKSNGV HTRIIWSCDW 540
  541 SHDGQFFVTS SRDGKVVVWK KE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.154902
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6.67009948605948 bayes_pls_golite062009
snoRNA binding 5.36667333535383 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
small conjugating protein ligase activity 3.13054264433898 bayes_pls_golite062009
ubiquitin-protein ligase activity 3.00646122159505 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
acid-amino acid ligase activity 2.17819869145391 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 1.4866444894826 bayes_pls_golite062009
structural molecule activity 1.47097979074281 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.21305848427711 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
ligase activity 0.93058496790047 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
transcription corepressor activity 0.182612389752591 bayes_pls_golite062009
chromatin binding 0.151977098745772 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [687-794] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDCKESSLNG WQANGVLELK NESITAVAFS NSYLSGTDDT YILALGTETG LIKIYQFVRG  60
   61 AWKLLSDLNK SQAHHLTVRR LQFRPGKQLQ LASCGEDHLV RIYDIKLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.221849
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle