| Protein: | EcR-PB, EcR-PG |
| Organism: | Drosophila melanogaster |
| Length: | 878 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EcR-PB, EcR-PG.
| Description | E-value | Query Range |
Subject Range |
|
|
431.0 | [0..226] | [878..17] |
|
Region A: Residues: [1-161] |
1 11 21 31 41 51
| | | | | |
1 MKRRWSNNGG FMRLPEESSS EVTSSSNGLV LPSGVNMSPS SLDSHDYCDQ DLWLCGNESG 60
61 SFGGSNGHGL SQQQQSVITL AMHGCSSTLP AQTTIIPING NANGNGGSTN GQYVPGATNL 120
121 GALANGMLNG GFNGMQQQIQ NGHGLINSTT PSTPTTPLHL Q
|
| Detection Method: |  |
| Confidence: | 12.045757 |
| Match: | 1i3qA |
| Description: | RBP1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [162-255] |
1 11 21 31 41 51
| | | | | |
1 QNLGGAGGGG IGGMGILHHA NGTPNGLIGV VGGGGGVGLG VGGGGVGGLG MQHTPRSDSV 60
61 NSISSGRDDL SPSSSLNGYS ANESCDAKKS KKGP
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [256-328] |
1 11 21 31 41 51
| | | | | |
1 APRVQEELCL VCGDRASGYH YNALTCEGCK GFFRRSVTKS AVYCCKFGRA CEMDMYMRRK 60
61 CQECRLKKCL AVG
|
| Detection Method: | |
| Confidence: | 31.221849 |
| Match: | 1r0nB |
| Description: | Crystal Structure of Heterodimeric Ecdsyone receptor DNA binding complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription regulator activity | 4.00967542385368 | bayes_pls_golite062009 |
| DNA binding | 3.60745514727532 | bayes_pls_golite062009 |
| nucleic acid binding | 3.47256374293954 | bayes_pls_golite062009 |
| binding | 2.96409924710655 | bayes_pls_golite062009 |
| transcription activator activity | 2.9532663930699 | bayes_pls_golite062009 |
| transcription factor activity | 2.90769972671972 | bayes_pls_golite062009 |
| molecular transducer activity | 2.85308229764446 | bayes_pls_golite062009 |
| signal transducer activity | 2.85308229764446 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 2.72967350701574 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.55186574506963 | bayes_pls_golite062009 |
| protein binding | 2.44501340584871 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 2.40923942043513 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 2.19264900659739 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.00119042792567 | bayes_pls_golite062009 |
| androgen receptor binding | 1.92232680714675 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 1.91348392022358 | bayes_pls_golite062009 |
| transcription repressor activity | 1.88834375049208 | bayes_pls_golite062009 |
| hormone receptor binding | 1.8288193687002 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.81056798510499 | bayes_pls_golite062009 |
| ligand-dependent nuclear receptor activity | 1.49515149729803 | bayes_pls_golite062009 |
| transcription factor binding | 1.38523780690867 | bayes_pls_golite062009 |
| steroid hormone receptor activity | 1.28090460550476 | bayes_pls_golite062009 |
| specific RNA polymerase II transcription factor activity | 1.26452462867497 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.26313925559554 | bayes_pls_golite062009 |
| structural molecule activity | 1.1947100233139 | bayes_pls_golite062009 |
| receptor activity | 1.05205471090697 | bayes_pls_golite062009 |
| transporter activity | 0.768214707487563 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.61572149323953 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.58115018700114 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.50876329665586 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.187612502757984 | bayes_pls_golite062009 |
| catalytic activity | 0.101795606736461 | bayes_pls_golite062009 |
|
Region A: Residues: [329-654] |
1 11 21 31 41 51
| | | | | |
1 MRPECVVPEN QCAMKRREKK AQKEKDKMTT SPSSQHGGNG SLASGGGQDF VKKEILDLMT 60
61 CEPPQHATIP LLPDEILAKC QARNIPSLTY NQLAVIYKLI WYQDGYEQPS EEDLRRIMSQ 120
121 PDENESQTDV SFRHITEITI LTVQLIVEFA KGLPAFTKIP QEDQITLLKA CSSEVMMLRM 180
181 ARRYDHSSDS IFFANNRSYT RDSYKMAGMA DNIEDLLHFC RQMFSMKVDN VEYALLTAIV 240
241 IFSDRPGLEK AQLVEAIQSY YIDTLRIYIL NRHCGDSMSL VFYAKLLSIL TELRTLGNQN 300
301 AEMCFSLKLK NRKLPKFLEE IWDVHA
|
| Detection Method: | |
| Confidence: | 51.0 |
| Match: | 1z5xE |
| Description: | hemipteran ecdysone receptor ligand-binding domain complexed with ponasterone A |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [655-878] |
1 11 21 31 41 51
| | | | | |
1 IPPSVQSHLQ ITQEENERLE RAERMRASVG GAITAGIDCD SASTSAAAAA AQHQPQPQPQ 60
61 PQPSSLTQND SQHQTQPQLQ PQLPPQLQGQ LQPQLQPQLQ TQLQPQIQPQ PQLLPVSAPV 120
121 PASVTAPGSL SAVSTSSEYM GGSAAIGPIT PATTSSITAA VTASSTTSAV PMGNGVGVGV 180
181 GVGGNVSMYA NAQTAMALMG VALHSHQEQL IGGVAVKSEH STTA
|
| Detection Method: | |
| Confidence: | 1.03 |
| Match: | 2j63A |
| Description: | No description for 2j63A was found. |
