YRC Public Data Repository - Protein Structure Prediction

Protein:	NFYB_RAT
Organism:	Rattus norvegicus
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NFYB_RAT.

Description	E-value	Query Range	Subject Range
gi\|60653441 - gi\|60653441\|gb\|AAX29415.1\| nuclear transcription factor Y beta [synthetic construct]	257.0	[0..1]	[207..1]
ENSMMUT000000317... - null, null NFYB - nuclear transcription factor Y, beta ENSCJAT00000028469 - null gi\|123993257, gi... - gi\|60656481\|gb\|AAX32804.1\| nuclear transcription factor Y beta [synthetic construct], gi\|208966894\|d...	256.0	[0..1]	[207..1]
gi\|73977777 - gi\|73977777\|ref\|XP_532675.2\| PREDICTED: similar to nuclear transcription factor-Y beta isoform 1 [Ca...	255.0	[0..1]	[207..1]
NFYB_HORSE - Nuclear transcription factor Y subunit beta OS=Equus caballus GN=NFYB PE=2 SV=1	255.0	[0..1]	[207..1]
gi\|741374 - gi\|741374\|prf\|\|2007263A CCAAT-binding factor	254.0	[0..1]	[207..1]
NFYB_BOVIN - Nuclear transcription factor Y subunit beta OS=Bos taurus GN=NFYB PE=2 SV=1	254.0	[0..1]	[207..1]
gi\|105492, gi\|35050 - gi\|35050\|emb\|CAA42230.1\| CAAT-box DNA binding protein subunit B (NF-YB) [Homo sapiens], gi\|105492\|pi... gi\|109098520, gi... - gi\|109098520\|ref\|XP_001097495.1\| PREDICTED: similar to Nuclear transcription factor Y subunit beta (...	252.0	[0..3]	[207..1]
NFYB_CHICK - Nuclear transcription factor Y subunit beta OS=Gallus gallus GN=NFYB PE=2 SV=2	252.0	[0..3]	[207..1]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE SFREQDIYLP  60
   61 IANVARIMKN AIPQTGKIAK DAKECVQECV SEFISFITSE ASERCHQEKR KTINGEDILF 120
  121 AMSTLGFDSY VEPLKLYLQK FREAMKGEKG IGGAVSATDG LSEELTEEAF TNQLPAGLIT 180
  181 ADGQQQNVMV YTTSYQQISG VQQIQFS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	1n1jA
Description:	Nuclear transcription factor Y subunit beta (Nf-Yb3)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA binding	4.49118409263799	bayes_pls_golite062009
nucleic acid binding	4.35201412176948	bayes_pls_golite062009
transcription regulator activity	4.08606081850613	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	4.04353148658823	bayes_pls_golite062009
binding	3.27510691458843	bayes_pls_golite062009
transcription activator activity	2.58408368884371	bayes_pls_golite062009
transcription factor activity	2.51581622888695	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.38228606466152	bayes_pls_golite062009
protein binding	2.1291876005999	bayes_pls_golite062009
sequence-specific DNA binding	1.18653213156155	bayes_pls_golite062009
transcription factor binding	1.15204005455906	bayes_pls_golite062009
transcription coactivator activity	1.1297723528047	bayes_pls_golite062009
transcription cofactor activity	1.01502031330902	bayes_pls_golite062009
transcription repressor activity	0.72554769377984	bayes_pls_golite062009
transcription initiation factor activity	0.0945459819298291	bayes_pls_golite062009
transcription corepressor activity	0.0736756545988504	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: