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View Structure Prediction Details

Protein: RU1C_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 182 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RU1C_SCHPO.

Description E-value Query
Range
Subject
Range
gi|67971420 - gi|67971420|dbj|BAE02052.1| unnamed protein product [Macaca fascicularis]
130.0 [0..1] [64..1]
gi|109458031 - gi|109458031|ref|XP_001076224.1| PREDICTED: similar to Protein CXorf17 homolog [Rattus norvegicus]
130.0 [0..1] [101..1]
gi|109070829 - gi|109070829|ref|XP_001111611.1| PREDICTED: similar to U1 small nuclear ribonucleoprotein C (U1 snRN...
128.0 [0..1] [64..166]
gi|108869989, gi... - gi|157136350|ref|XP_001663716.1| hypothetical protein AaeL_AAEL013527 [Aedes aegypti], gi|108869989|...
128.0 [0..1] [105..1]
gi|125775241, gi... - gi|54638613|gb|EAL28015.1| GA18892 [Drosophila pseudoobscura pseudoobscura], gi|125775241|ref|XP_001...
gi|194102311, gi... - gi|195144768|ref|XP_002013368.1| GL24104 [Drosophila persimilis], gi|194102311|gb|EDW24354.1| GL2410...
RU1C_DROPS - U1 small nuclear ribonucleoprotein C OS=Drosophila pseudoobscura pseudoobscura GN=snRNP-U1-C PE=3 SV...
127.0 [0..1] [91..1]
gi|58395833, gi|... - gi|58395833|ref|XP_321527.2| AGAP001584-PA [Anopheles gambiae str. PEST], gi|55233767|gb|EAA00983.2|...
RU1C_ANOGA - U1 small nuclear ribonucleoprotein C OS=Anopheles gambiae GN=AGAP001584 PE=3 SV=2
127.0 [0..1] [105..1]
gi|19577373 - gi|19577373|emb|CAD27755.1| putative sRNP [Anopheles gambiae]
126.0 [0..1] [104..1]
gi|73972600 - gi|73972600|ref|XP_532115.2| PREDICTED: similar to U1 small nuclear ribonucleoprotein C (U1 snRNP pr...
120.0 [0..1] [64..90]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRYLCDYCQ VWLTHDSQSV RKAHNAGRAH IQNVQDYYTK VAQEEAQKQL EERASSGFLK  60
   61 KGNGSLDLPY AYAFPPKYNV FNLGCP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1uw2A
Description: The structure of the zinc finger from the human spliceosomal protein U1C
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
U1 snRNA binding 4.35911393951689 bayes_pls_golite062009
transcription regulator activity 3.60566283434269 bayes_pls_golite062009
DNA binding 3.55661236227495 bayes_pls_golite062009
nucleic acid binding 3.48507500696529 bayes_pls_golite062009
snRNA binding 3.38579636849163 bayes_pls_golite062009
RNA binding 3.1651307444578 bayes_pls_golite062009
transcription factor activity 2.66585743129629 bayes_pls_golite062009
binding 2.51459778938853 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.8286807075508 bayes_pls_golite062009
transcription activator activity 1.42518458564872 bayes_pls_golite062009
mRNA binding 1.30742677372942 bayes_pls_golite062009
chromatin binding 0.89589330553881 bayes_pls_golite062009
sequence-specific DNA binding 0.8936929860974 bayes_pls_golite062009
transcription repressor activity 0.882178479686399 bayes_pls_golite062009
transcription factor binding 0.67452735768188 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.47352407708364 bayes_pls_golite062009
protein binding 0.308413944574415 bayes_pls_golite062009
transcription cofactor activity 0.26487559807277 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009
structure-specific DNA binding 0.240825841910931 bayes_pls_golite062009
double-stranded DNA binding 0.0129353639725593 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-182]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPYIVSANT YMAPKGMNAM NAAAFVPMMP AVNLTNQVAF SAPQTTASSN TQLTQQQQSL  60
   61 PQTNEHQRAR THSNANNHFT KTHHQGQRSH QRFVRA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle