| Protein: | TYSY_SCHPO |
| Organism: | Schizosaccharomyces pombe 972h- |
| Length: | 625 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TYSY_SCHPO.
| Description | E-value | Query Range |
Subject Range |
|
|
467.0 | [0..197] | [625..115] |
|
|
464.0 | [0..155] | [625..65] |
|
|
459.0 | [0..212] | [625..167] |
|
|
459.0 | [0..199] | [625..113] |
|
|
458.0 | [0..143] | [625..77] |
|
|
458.0 | [0..135] | [625..59] |
|
|
457.0 | [0..155] | [625..65] |
|
|
454.0 | [0..143] | [625..67] |
|
Region A: Residues: [1-217] |
1 11 21 31 41 51
| | | | | |
1 MSQPLHARFA TRAVKNPMIL EKERQLTDSK YHILVAATGS VAAIKLTLIV KSLLTYKGVD 60
61 VQVVLTDPAR NFVEKEDLTA LGVNVYNNAD DWKNWDGLEC PITHIELRRW AHLLLIAPLS 120
121 ANTMAKMANG LCDNLLTSLI RAWAPLKPIL LAPAMNTLMW TNPITQEHLS AISRIYKNSE 180
181 FIMPIEKVLA CGDIGMGGMA EWRNIVGRVA DKLQLEQ
|
| Detection Method: |  |
| Confidence: | 57.522879 |
| Match: | 1qzuA |
| Description: | crystal structure of human phosphopantothenoylcysteine decarboxylase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphopantothenoylcysteine decarboxylase activity | 3.86093811191169 | bayes_pls_golite062009 |
| phosphopantothenate--cysteine ligase activity | 2.64345867885176 | bayes_pls_golite062009 |
| binding | 1.79334633421708 | bayes_pls_golite062009 |
| carboxy-lyase activity | 1.79168084682693 | bayes_pls_golite062009 |
| catalytic activity | 1.51672397362026 | bayes_pls_golite062009 |
| carbon-carbon lyase activity | 1.03827559540394 | bayes_pls_golite062009 |
| protein binding | 0.359358565373414 | bayes_pls_golite062009 |
|
Region A: Residues: [218-327] |
1 11 21 31 41 51
| | | | | |
1 KSVLPNAVKN IDGQDDDSSE QTAAFEEYDD DDDDDVDDNE QSNSMIETSA NADITPKASL 60
61 LPSTTESSIS KDHETSQAPL GSESVDTQAS ENVTTKPEPP VPFTSSEYRN
|
| Detection Method: | |
| Confidence: | 42.0 |
| Match: | 1u7uA |
| Description: | Phosphopantothenoylcysteine synthetase from E. coli |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [328-625] |
1 11 21 31 41 51
| | | | | |
1 TEEEQYLNLI RYILENGQSR PDRTGTGTRS VFAPPQLRFS LRNNTLPLLT TKRVFLRGVL 60
61 EELLWFIHGD TNANHLSEKG IHIWDGNGSR EFLDSRGLTD RKVGDLGPIY GFQWRHFGAQ 120
121 YVDCDTDYTN KGVDQLAQVI STLKLNPYDR RIILSAWNPL AIPEMALPPC HIFCQFYVSE 180
181 PCKPGGKPQL SSMMYQRSAD MGLGVPFNIA SYSLLTHMIA HMCGYEAAEF VHVMGDCHIY 240
241 NDHLEALQTQ LERVPKAFPK LFFKRDAKDI GSIDSFSVDD FAVEGYNPYG PIKMKMSV
|
| Detection Method: | |
| Confidence: | 118.0 |
| Match: | 1ci7A |
| Description: | Thymidylate synthase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| thymidylate synthase activity | 6.6988475347328 | bayes_pls_golite062009 |
| 5,10-methylenetetrahydrofolate-dependent methyltransferase activity | 6.29181090719132 | bayes_pls_golite062009 |
| binding | 1.89072001556053 | bayes_pls_golite062009 |
| catalytic activity | 1.73427871128495 | bayes_pls_golite062009 |
| transferase activity | 1.72626940963556 | bayes_pls_golite062009 |
| methyltransferase activity | 0.927096828883487 | bayes_pls_golite062009 |
| transferase activity, transferring one-carbon groups | 0.91282507161672 | bayes_pls_golite062009 |
