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Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate. Catalysis of the transfer of a methyl group to an acceptor molecule. Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: thymidylate synthase activity
Acc: GO:0004799
Aspect: Molecular Function
Desc: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
Synonyms:
  • thymidylate synthetase activity
  • TMP synthetase activity
  • 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity
  • methylenetetrahydrofolate:dUMP C-methyltransferase activity
  • dTMP synthase activity
Proteins in PDR annotated with:
   This term: 19 [Search]
   Term or descendants: 19 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004799 - thymidylate synthase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle