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Protein Overview: gi|77550896

General Information:
Name(s) found: gi|77550896 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • gi|77550896|gb|ABA93693.1| Bifunctional dihydrofolate reductase-thymidylate synthase, putative, expressed [Oryza sativa (japonica cultivar-group)] [NCBI NR]
    • Organism: Oryza sativa Japonica Group
    Length: 521 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATTLSNGVS QNGPQRNYQV VVAATRDMGI GKDGVLPWKL LGDLKFFKEL TVTTADPVKK  60
   61 NAVIMGRKTW ESLPLKARPL PGRLNIILTR SGSFEFATVE NVVICGSMNS ALELLSSTPY 120
  121 CLSIEKVFVI GGGQVLRESL NGPSCEAVHL TDIQSSIECD TFIPPIDLSV FQPWYSSLPV 180
  181 VESNIRHSFV TYVRVRKTMA ETHDSNGKES ANDGIKSDKF ETENFSFLPK LIFDRHEEYH 240
  241 YLNLVEDIIR SGAQKNDRTG TGTLSKFGCQ MRFNLRNSFP LLTTKKVFWR GVVEELLWFI 300
  301 SGSTSAKVLQ EKGIHIWDGN ASREYLDSVG LAHREEGDLG PVYGFQWRHF GAEYTDMHAD 360
  361 YTGKGFDQLM DVIDKIKNNP DDRRIILSAW NPSDLKKMAL PPCHMFAQFY VESGELSCQM 420
  421 YQRSADMGLG VPFNIASYSL LTYMIAHVCG LSPGEFVHVI GDAHVYRTHV RALEEQIQKL 480
  481 PKPFPVLKIN PLKKDIDSFV ASDFKLVGYD PHQKIEMKMA I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..521] PSI-BLAST 171.0 Crystal structure of DHFR-TS from Cryptosporidium hominis

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • thymidylate synthase activity
    		•  6.6988475347328 bayes_pls_golite062009
  • 5,10-methylenetetrahydrofolate-dependent methyltransferase activity
    		•  6.29181090719132 bayes_pls_golite062009
  • dihydrofolic acid binding
    		•  5.17709559620199 bayes_pls_golite062009
  • dihydrofolate reductase activity
    		•  4.66343252900911 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  4.14137539326183 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  3.88025481634404 bayes_pls_golite062009
  • methyltransferase activity
    		•  2.19378329702464 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.11989367906451 bayes_pls_golite062009
  • binding
    		•  1.89072001556053 bayes_pls_golite062009
  • catalytic activity
    		•  1.73427871128495 bayes_pls_golite062009
  • transferase activity
    		•  1.72626940963556 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.63757996555211 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle