YRC Public Data Repository - Protein Structure Prediction

Protein:	CSL4_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CSL4_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|20089605, gi\|... - gi\|20089605\|ref\|NP_615680.1\| hypothetical protein MA0720 [Methanosarcina acetivorans C2A], gi\|199145...	162.0	[0..3]	[178..130]
gi\|18891956, gi\|... - gi\|18976424\|ref\|NP_577781.1\| exosome complex RNA-binding protein Csl4 [Pyrococcus furiosus DSM 3638]...	158.0	[0..2]	[178..13]
gi\|73669146, gi\|... - gi\|73669146\|ref\|YP_305161.1\| putative RNA-binding protein [Methanosarcina barkeri str. Fusaro], gi\|7...	158.0	[0..3]	[178..137]
gi\|14520270, gi\|... - gi\|5457485\|emb\|CAB48976.1\| RNA-binding protein, putative, containing S1 RNA binding domain [Pyrococc... gi\|7445291, gi\|5... - pir\|\|A75191 hypothetical protein PAB2314 - Pyrococcus abyssi (strain Orsay), gi\|5457485\|emb\|CAB48976...	156.0	[0..2]	[178..15]
gi\|20906407, gi\|... - gi\|21227981\|ref\|NP_633903.1\| putative RNA-binding protein [Methanosarcina mazei Go1], gi\|20906407\|gb...	156.0	[0..3]	[178..135]
gi\|7429750 - pir\|\|H71222 hypothetical protein PH0043 - Pyrococcus horikoshii gi\|3256428, gi\|1... - gi\|3256428\|dbj\|BAA29111.1\| 200aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14589998\|...	151.0	[0..2]	[178..15]
gi\|57159428, gi\|... - gi\|57641104\|ref\|YP_183582.1\| exosome complex RNA-binding protein Csl4 [Thermococcus kodakarensis KOD...	147.0	[0..2]	[178..11]
gi\|124301132, gi... - gi\|42568189\|ref\|NP_568559.2\| exoribonuclease-related [Arabidopsis thaliana], gi\|222423301\|dbj\|BAH196...	144.0	[0..3]	[176..5]
EXOSC1 - exosome component 1 gi\|114632191 - gi\|114632191\|ref\|XP_507960.2\| PREDICTED: similar to CGI-108 protein [Pan troglodytes] CCDS7459.1_1 - null gi\|208966238 - gi\|208966238\|dbj\|BAG73133.1\| exosome component 1 [synthetic construct] gi\|109090153 - gi\|109090153\|ref\|XP_001103710.1\| PREDICTED: exosome component 1 [Macaca mulatta]	143.0	[0..2]	[176..6]
gi\|59858307, gi\|... - gi\|62751675\|ref\|NP_001015529.1\| exosomal core protein CSL4 [Bos taurus], gi\|59858307\|gb\|AAX08988.1\| ...	143.0	[0..2]	[176..6]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLVLPGQVV ARGAPNGEGT VKRGDYIIST RTGIFDPEKN SVTYPRKVEE TAVLPNVGSI  60
   61 VLARVSRINA RQATVNISVV DDVCTKDEFQ GVIHVQDIRA TEKNKVKVQN SFRPGDIVRA 120
  121 LVISLGDGSS YFLTTARNDL GVIFAQSSET GEQMFPVDYQ HMQTKSGYTE MRKCAKPILD 180
  181 E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.69897
Match:	2nn6I
Description:	No description for 2nn6I was found.

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	7.42330864261751	bayes_pls_golite062009
exoribonuclease activity	6.76241588209982	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	6.73428326869965	bayes_pls_golite062009
3'-5'-exoribonuclease activity	5.13367897180134	bayes_pls_golite062009
structural constituent of ribosome	4.51084463039261	bayes_pls_golite062009
structural molecule activity	4.29692945022158	bayes_pls_golite062009
3'-5' exonuclease activity	3.51306349336452	bayes_pls_golite062009
nucleic acid binding	3.194200758646	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3.07263153665399	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.73968547121328	bayes_pls_golite062009
DNA binding	2.71213098011194	bayes_pls_golite062009
exonuclease activity	2.66053639652924	bayes_pls_golite062009
RNA binding	2.41160981373213	bayes_pls_golite062009
binding	2.24181355929217	bayes_pls_golite062009
structure-specific DNA binding	1.81524862921454	bayes_pls_golite062009
single-stranded DNA binding	1.62996999055328	bayes_pls_golite062009
	1.5765009871268	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	1.35850109411274	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	1.35845277283398	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	1.35845277283398	bayes_pls_golite062009
exoribonuclease II activity	1.18248519339188	bayes_pls_golite062009
transcription regulator activity	0.996884322431837	bayes_pls_golite062009
hydrolase activity	0.724860465280978	bayes_pls_golite062009
nuclease activity	0.57381531077345	bayes_pls_golite062009
mRNA binding	0.4162128308402	bayes_pls_golite062009
ligase activity	0.346041081217685	bayes_pls_golite062009
sequence-specific DNA binding	0.32084431704638	bayes_pls_golite062009
transcription factor activity	0.298729064067577	bayes_pls_golite062009
translation regulator activity	0.22908707234671	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.179682348023561	bayes_pls_golite062009
catalytic activity	0.161830442565647	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.151650064901878	bayes_pls_golite062009
telomeric DNA binding	0.150235510823939	bayes_pls_golite062009
translation initiation factor activity	0.11625379846973	bayes_pls_golite062009
DNA-directed RNA polymerase activity	0.0740938021136293	bayes_pls_golite062009
RNA polymerase activity	0.0740938021136293	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: